02531naa a2200325 a 450000100080000000500110000800800410001902400360006010000150009624501940011126000090030550000700031452014310038465300200181565300230183565300100185865300110186865300120187965300210189165300490191265300310196170000150199270000250200770000170203270000180204970000180206770000220208570000170210777300810212410623372022-09-02 2021 bl uuuu u00u1 u #d7 a10.1007/s00436-021-07248-y2DOI1 aDORSCH, M. aMorphometric study of encephalic lesions in aborted bovine fetuses naturally infected by two subpopulations of Neospora caninum. (Protozoology - Short Communication).h[electronic resource] c2021 aArticle History: Received: 10 June 2021 / Accepted: 12 July 2021. aAbstract: Neospora caninum is a major reproductive disease in cattle worldwide. In the Argentinian Humid Pampa, the seroprevalence, incidence of abortions, and economic losses due to neosporosis are considerably higher in dairy than in beef cattle. Despite this, we recently demonstrated that N. caninum subpopulations are indistinctly distributed in both dairy and beef production systems. The association between genotypic characteristics defned by microsatellite analysis and the virulence of the different strains?particularly with regard to the severity and extension of histological lesions?is largely unknown. Herein, we used a morphometric approach to analyze encephalic lesions in 62 bovine fetuses spontaneously infected by N. caninum. Morphometric parameters (average size of focal lesions, number of foci/cm2 and the percentage of the section afected by lesions) were compared according to the N. caninum subpopulations found in our previous microsatellite genotyping analysis, animal biotype (beef versus dairy), and fetal age (second stage of gestation versus third stage). The average size of the lesions difered signifcantly among fetuses with diferent gestational ages; however, no signifcant diferences among animal biotypes or genotypic patterns were found. Further research into the genetic, molecular, and husbandry factors that could account for this greater impact in Argentinian dairy herds is needed. aAborted fetuses aAssociated factors aBRAIN aCattle aLesions aNeospora caninum aPLATAFORMA DE INVESTIGACIÓN EN SALUD ANIMAL aPLATAFORMA DE SALUD ANIMAL1 aMOORE, D.P1 aREGIDOR-CERRILLO, J.1 aSCIOLI, M.V.1 aMORRELL, E.L.1 aCANTÓN, G.J.1 aORTEGA-MORA, L.M.1 aHECKER, Y.P. tParasitology Research, 2021. Doi: https://doi.org/10.1007/s00436-021-07248-y