02641naa a2200337 a 450000100080000000500110000800800410001902400350006010000190009524501270011426000090024152015880025065300100183865300200184865300490186865300310191765300250194865300210197370000170199470000130201170000180202470000170204270000130205970000170207270000190208970000130210870000160212170000150213770000140215277301370216610626482022-03-18 2022 bl uuuu u00u1 u #d7 a10.1177/104063872110611432DOI1 aCLOTHIER, K.A. aGeneralized dermatophytosis caused by Trichophyton equinum in 8 juvenile black bears in California.h[electronic resource] c2022 aAbstract. From 2014?2019, 8 juvenile black bears (Ursus americanus) from different geographic regions were presented to the California Department of Fish and Wildlife because of emaciation, alopecia, and exfoliative dermatitis that resulted in death or euthanasia. Autopsy and histopathology revealed that all 8 bears had generalized hyperkeratotic dermatitis, folliculitis, and furunculosis. Skin structures were heavily colonized by fungal hyphae and arthrospores; fungal cultures of skin from 7 bears yielded Trichophyton equinum, a zoophilic dermatophyte reported only rarely in non-equid species. Additional skin conditions included mites (5), ticks (2), and coagulase-negative Staphylococcus sp. infections (2). No other causes of morbidity or mortality were identified. Molecular comparisons performed at the University of Texas Fungal Reference Laboratory determined that all isolates produced identical banding patterns, potentially representing a clonal population. Dermatophytosis is commonly localized and limited to the stratum corneum of the epidermis and hair follicles. Generalized disease with dermal involvement is rare in immunocompetent individuals; illness, malnutrition, age, or immunosuppression may increase susceptibility. Underlying causes for the severe disease impact in these bears were not evident after physical or postmortem examination. The mechanism by which bears from different geographic locations had severe, T. equinum?associated dermatophytosis from a potentially clonal dermatophyte could not be explained and warrants further investigation. aBears aDermatophytosis aPLATAFORMA DE INVESTIGACIÓN EN SALUD ANIMAL aPLATAFORMA DE SALUD ANIMAL aTrichophyton equinum aUrsus americanus1 aWATSON, K.D.1 aMETE, A.1 aGIANNITTI, F.1 aANDERSON, M.1 aMUNK, B.1 aMCMILLIN, S.1 aCLIFFORD, D.L.1 aRUDD, J.1 aSHIRKEY, N.1 aFAMINI, D.1 aWOODS, L. tJournal of Veterinary Diagnostic Investigation, 2022, Volume 34, Issue 2, pp.279-283. doi: https://doi.org/10.1177/10406387211061143