| |
|
|
| Registros recuperados : 2 | |
| Registros recuperados : 2 | |
|
|
|
 | Acceso al texto completo restringido a Biblioteca INIA Las Brujas. Por información adicional contacte bibliolb@inia.org.uy. |
|
Registro completo
|
|
Biblioteca (s) : |
INIA Las Brujas. |
|
Fecha actual : |
08/09/2022 |
|
Actualizado : |
01/12/2022 |
|
Tipo de producción científica : |
Artículos en Revistas Indexadas Internacionales |
|
Circulación / Nivel : |
Internacional - -- |
|
Autor : |
VASINI, B.; FARACE, P.; ARIEL, A.; CIRONE, K.; MÉNDEZ, L.; MORSELLA, C.; FRESIA, P.; IRAOLA, G.; GIOFFRÉ, A.; PAOLICCHI, F. |
|
Afiliación : |
BRENDA VASINI, Laboratorio de Bacteriología-Grupo de Sanidad Animal, Unidad Integrada INTA-Universidad Nacional de Mar del Plata-Balcarce, Bs.As., Argentina; Consejo Nacional de Investigaciones Científicas y Tecnológicas (CONICET), Bs.As., Argentina; PABLO FARACE, Consejo Nacional de Investigaciones Científicas y Tecnológicas (CONICET), Bs.As., Argentina; Instituto de Agrobiotecnología y Biología Molecular (IABIMO), Instituto Nacional de Tecnología Agropecuaria (INTA), Bs.As., Argentina; AMADIO ARIEL, Consejo Nacional de Investigaciones Científicas y Tecnológicas (CONICET), Bs.As., Argentina; KARINA CIRONE, Laboratorio de Bacteriología-Grupo de Sanidad Animal, Unidad Integrada INTA-Universidad Nacional de Mar del Plata-Balcarce, Bs.As., Argentina; LAURA MÉNDEZ, Laboratorio de Bacteriología-Grupo de Sanidad Animal, Unidad Integrada INTA-Universidad Nacional de Mar del Plata-Balcarce, Bs.As., Argentina; CLAUDIA MORSELLA, Laboratorio de Bacteriología-Grupo de Sanidad Animal, Unidad Integrada INTA-Universidad Nacional de Mar del Plata-Balcarce, Bs.As., Argentina; PABLO FRESIA, Unidad Mixta UMPI, Institut Pasteur Montevideo + INIA, Montevideo, Uruguay; Microbial Genomics Laboratory, Institut Pasteur Montevideo, Montevideo, Uruguay; GREGORIO IRAOLA, Microbial Genomics Laboratory, Institut Pasteur Montevideo, Montevideo, Uruguay; Center for Integrative Biology, Universidad Mayor, Santiago de Chile, Chile; Wellcome Sanger Institute, Hinxton, United Kingdom; ANDREA GIOFFRÉ, Consejo Nacional de Investigaciones Científicas y Tecnológicas (CONICET), Bs.As., Argentina; Instituto de Agrobiotecnología y Biología Molecular (IABIMO), Instituto Nacional de Tecnología Agropecuaria (INTA), Bs.As., Argentina; FERNANDO PAOLICCHI, Laboratorio de Bacteriología-Grupo de Sanidad Animal, Unidad Integrada INTA-Universidad Nacional de Mar del Plata-Balcarce, Bs.As., Argentina. |
|
Título : |
Phylogenetic and multiple-locus variable number tandem repeat analysis of Mycobacterium avium subsp. paratuberculosis isolates from Argentina. |
|
Fecha de publicación : |
2022 |
|
Fuente / Imprenta : |
Veterinary Research Communications, December 2022, Volume 46, Issue 4, pages 1121-1129. doi: https://doi.org/10.1007/s11259-022-09983-8 |
|
ISSN : |
0165-7380 |
|
DOI : |
10.1007/s11259-022-09983-8 |
|
Idioma : |
Inglés |
|
Notas : |
Article history: Received 24 February 2022; Accepted 3 August 2022. -- Corresponding author: Vasini, B.; Laboratorio de Bacteriología-Grupo de Sanidad Animal, Unidad Integrada INTA-Universidad Nacional de Mar del Plata-Balcarce, Buenos Aires, Argentina; email:vasinibrenda@gmail.com --
Founding: This study was funded by ANPCyT (PICT grant, project PICT2015-1541), CONICET (PIP grant, project PIP11220150100316CO) and INTA (project 2019-PD-E5-I103-001). |
|
Contenido : |
ABSTRACT.- Paratuberculosis is a worldwide chronic enteric disease of ruminants, caused by Mycobacterium avium subsp. paratuberculosis (MAP). While MAP has been widely investigated all around the world, little is known about the different strains that circulate in each country. This study describes the genetic diversity of MAP isolates from different bovine and deer herds from Argentina, analyzed by Multiple-Locus Variable number tandem repeat Analysis (MLVA), as well as the phylogenetic relatedness between geographically distant isolates through Whole Genome Sequencing (WGS) and core-genome analysis. A total of 90 MAP isolates were analyzed. The results showed seven different MLVA genotypes, with almost 75% of them belonging to pattern INMV 1, described in all the herds studied. WGS results suggested the presence of a common INMV 1 strain circulating throughout the country. Our results allow confirming the coexistence of different strains in time and space and the mixed infections identified in some animals. These observations suggest the absence of animal monitoring prior to introduction to the herds and the need for a control program in the country. This study represents the first to report WGS of MAP strains in Argentina. © 2022, The Author(s), under exclusive licence to Springer Nature B.V. |
|
Palabras claves : |
MLVA; Mycobacterium; Ruminants; UNIDAD MIXTA PASTEUR + INIA; WGS. |
|
Asunto categoría : |
L10 Genética y mejoramiento animal |
|
Marc : |
LEADER 02775naa a2200325 a 4500
001 1063566
005 2022-12-01
008 2022 bl uuuu u00u1 u #d
022 $a0165-7380
024 7 $a10.1007/s11259-022-09983-8$2DOI
100 1 $aVASINI, B.
245 $aPhylogenetic and multiple-locus variable number tandem repeat analysis of Mycobacterium avium subsp. paratuberculosis isolates from Argentina.$h[electronic resource]
260 $c2022
500 $aArticle history: Received 24 February 2022; Accepted 3 August 2022. -- Corresponding author: Vasini, B.; Laboratorio de Bacteriología-Grupo de Sanidad Animal, Unidad Integrada INTA-Universidad Nacional de Mar del Plata-Balcarce, Buenos Aires, Argentina; email:vasinibrenda@gmail.com -- Founding: This study was funded by ANPCyT (PICT grant, project PICT2015-1541), CONICET (PIP grant, project PIP11220150100316CO) and INTA (project 2019-PD-E5-I103-001).
520 $aABSTRACT.- Paratuberculosis is a worldwide chronic enteric disease of ruminants, caused by Mycobacterium avium subsp. paratuberculosis (MAP). While MAP has been widely investigated all around the world, little is known about the different strains that circulate in each country. This study describes the genetic diversity of MAP isolates from different bovine and deer herds from Argentina, analyzed by Multiple-Locus Variable number tandem repeat Analysis (MLVA), as well as the phylogenetic relatedness between geographically distant isolates through Whole Genome Sequencing (WGS) and core-genome analysis. A total of 90 MAP isolates were analyzed. The results showed seven different MLVA genotypes, with almost 75% of them belonging to pattern INMV 1, described in all the herds studied. WGS results suggested the presence of a common INMV 1 strain circulating throughout the country. Our results allow confirming the coexistence of different strains in time and space and the mixed infections identified in some animals. These observations suggest the absence of animal monitoring prior to introduction to the herds and the need for a control program in the country. This study represents the first to report WGS of MAP strains in Argentina. © 2022, The Author(s), under exclusive licence to Springer Nature B.V.
653 $aMLVA
653 $aMycobacterium
653 $aRuminants
653 $aUNIDAD MIXTA PASTEUR + INIA
653 $aWGS
700 1 $aFARACE, P.
700 1 $aARIEL, A.
700 1 $aCIRONE, K.
700 1 $aMÉNDEZ, L.
700 1 $aMORSELLA, C.
700 1 $aFRESIA, P.
700 1 $aIRAOLA, G.
700 1 $aGIOFFRÉ, A.
700 1 $aPAOLICCHI, F.
773 $tVeterinary Research Communications, December 2022, Volume 46, Issue 4, pages 1121-1129. doi: https://doi.org/10.1007/s11259-022-09983-8
Descargar
Esconder MarcPresentar Marc Completo |
|
Registro original : |
INIA Las Brujas (LB) |
|
|
Biblioteca
|
Identificación
|
Origen
|
Tipo / Formato
|
Clasificación
|
Cutter
|
Registro
|
Volumen
|
Estado
|
Volver
|
| Expresión de búsqueda válido. Check! |
|
|
