| |
|
|
 | Acceso al texto completo restringido a Biblioteca INIA Las Brujas. Por información adicional contacte bibliolb@inia.org.uy. |
|
Registro completo
|
|
Biblioteca (s) : |
INIA Las Brujas. |
|
Fecha : |
11/09/2014 |
|
Actualizado : |
30/10/2019 |
|
Tipo de producción científica : |
Artículos en Revistas Indexadas Internacionales |
|
Autor : |
LOURENCO, D.A.L.; MISZTAL, I.; WANG, H.; AGUILAR, I.; TSURUTA, S.; BERTRAND, J.K. |
|
Afiliación : |
IGNACIO AGUILAR GARCIA, Instituto Nacional de Investigación Agropecuaria (INIA), Uruguay. |
|
Título : |
Prediction accuracy for a simulated maternally affected trait of beef cattle using different genomic evaluation models. |
|
Fecha de publicación : |
2013 |
|
Fuente / Imprenta : |
Journal of Animal Science, 2013, v.91, no.9, p.4090-4098. |
|
ISSN : |
0021-8812 |
|
DOI : |
10.2527/jas.2012-5826 |
|
Idioma : |
Inglés |
|
Notas : |
Article history: Published online July 26, 2013.
This study was partially funded by the American Angus Association (St. Joseph, MO) and the USDA Agriculture and Food Research Initiative (Grant no. 2009-65205-05665 from the USDA National Institute of Food and Agriculture Animal Genome Program). Helpful comments and suggestions from W. M. Snelling (U.S. Meat Animal Research Center, ARS, USDA, Clay Center, NE) and two anonymous reviewers are gratefully acknowledged. |
|
Contenido : |
ABSTRACT.
Different methods for genomic evaluation were compared for accuracy and feasibility of evaluation using phenotypic, pedigree, and genomic information for a trait influenced by a maternal effect. A simulated population was constructed that included 15,800 animals in 5 generations. Genotypes from 45,000 SNP were available for 1,500 animals in the last 3 generations. Genotyped animals in the last generation had no phenotypes. Weaning weight data were simulated using an animal model with direct and maternal effects. Additive direct and maternal effects were considered either noncorrelated (Graphic) or negatively correlated (Graphic). Methods of analysis were traditional BLUP, BayesC using phenotypes and ignoring maternal effects (BayesCPR), BayesC using deregressed EBV (BayesCDEBV), and single-step genomic BLUP (ssGBLUP). Whereas BayesCPR can be used when phenotypes of only genotyped animals are available, BayesCDEBV can be used when BLUP EBV of genotyped animals are available, and ssGBLUP is suitable when genotypes, phenotypes, and pedigrees are jointly available. For all genotyped and young genotyped animals, mean accuracies from BayesCPR and BayesCDEBV were lower than accuracies from BLUP for direct and maternal effects. The differences in mean accuracy were greater when genetic correlation was negative. Gains in accuracy were observed when ssGBLUP was compared with BLUP; for the direct (maternal) effect the average gain was 0.01 (0.02) for all genotyped animals and 0.03 (0.02) for young genotyped animals without phenotypes. Similar gains were observed for 0 and negative genetic correlation. Accuracy with BayesCPR was affected by ignoring phenotypes of nongenotyped animals and maternal effect and by not accounting for parent average. Accuracy with BayesCDEBV was affected by approximations needed for deregression, not accounting for parent average, and sequential rather than simultaneous fitting of genomic and nongenomic information. Whereas BayesCDEBV presented a considerable bias, especially for maternal effect, ssGBLUP was unbiased for both effects. The computing time was 1 s for BLUP, 44 s for ssGBLUP, and over 2,000 s for BayesC. Greatest computational efficiency and accuracy of genomic prediction for a maternally affected trait was obtained when information from all nongenotyped but related individuals was included and phenotypes, pedigree, and genotypes were available and considered jointly. Increasing the gain in accuracy of genomic predictions obtained by ssGBLUP over BLUP may require an increase in the number of genotyped animals. MenosABSTRACT.
Different methods for genomic evaluation were compared for accuracy and feasibility of evaluation using phenotypic, pedigree, and genomic information for a trait influenced by a maternal effect. A simulated population was constructed that included 15,800 animals in 5 generations. Genotypes from 45,000 SNP were available for 1,500 animals in the last 3 generations. Genotyped animals in the last generation had no phenotypes. Weaning weight data were simulated using an animal model with direct and maternal effects. Additive direct and maternal effects were considered either noncorrelated (Graphic) or negatively correlated (Graphic). Methods of analysis were traditional BLUP, BayesC using phenotypes and ignoring maternal effects (BayesCPR), BayesC using deregressed EBV (BayesCDEBV), and single-step genomic BLUP (ssGBLUP). Whereas BayesCPR can be used when phenotypes of only genotyped animals are available, BayesCDEBV can be used when BLUP EBV of genotyped animals are available, and ssGBLUP is suitable when genotypes, phenotypes, and pedigrees are jointly available. For all genotyped and young genotyped animals, mean accuracies from BayesCPR and BayesCDEBV were lower than accuracies from BLUP for direct and maternal effects. The differences in mean accuracy were greater when genetic correlation was negative. Gains in accuracy were observed when ssGBLUP was compared with BLUP; for the direct (maternal) effect the average gain was 0.01 (0.02) for all genotyped animals an... Presentar Todo |
|
Thesagro : |
GANADERÍA; GANADO DE CARNE; MEJORAMIENTO GENÉTICO ANIMAL; MODELOS DE SIMULACIÓN; SELECCIÓN GENÓMICA. |
|
Asunto categoría : |
L01 Ganadería |
|
Marc : |
LEADER 03895naa a2200277 a 4500
001 1050147
005 2019-10-30
008 2013 bl uuuu u00u1 u #d
022 $a0021-8812
024 7 $a10.2527/jas.2012-5826$2DOI
100 1 $aLOURENCO, D.A.L.
245 $aPrediction accuracy for a simulated maternally affected trait of beef cattle using different genomic evaluation models.$h[electronic resource]
260 $c2013
500 $aArticle history: Published online July 26, 2013. This study was partially funded by the American Angus Association (St. Joseph, MO) and the USDA Agriculture and Food Research Initiative (Grant no. 2009-65205-05665 from the USDA National Institute of Food and Agriculture Animal Genome Program). Helpful comments and suggestions from W. M. Snelling (U.S. Meat Animal Research Center, ARS, USDA, Clay Center, NE) and two anonymous reviewers are gratefully acknowledged.
520 $aABSTRACT. Different methods for genomic evaluation were compared for accuracy and feasibility of evaluation using phenotypic, pedigree, and genomic information for a trait influenced by a maternal effect. A simulated population was constructed that included 15,800 animals in 5 generations. Genotypes from 45,000 SNP were available for 1,500 animals in the last 3 generations. Genotyped animals in the last generation had no phenotypes. Weaning weight data were simulated using an animal model with direct and maternal effects. Additive direct and maternal effects were considered either noncorrelated (Graphic) or negatively correlated (Graphic). Methods of analysis were traditional BLUP, BayesC using phenotypes and ignoring maternal effects (BayesCPR), BayesC using deregressed EBV (BayesCDEBV), and single-step genomic BLUP (ssGBLUP). Whereas BayesCPR can be used when phenotypes of only genotyped animals are available, BayesCDEBV can be used when BLUP EBV of genotyped animals are available, and ssGBLUP is suitable when genotypes, phenotypes, and pedigrees are jointly available. For all genotyped and young genotyped animals, mean accuracies from BayesCPR and BayesCDEBV were lower than accuracies from BLUP for direct and maternal effects. The differences in mean accuracy were greater when genetic correlation was negative. Gains in accuracy were observed when ssGBLUP was compared with BLUP; for the direct (maternal) effect the average gain was 0.01 (0.02) for all genotyped animals and 0.03 (0.02) for young genotyped animals without phenotypes. Similar gains were observed for 0 and negative genetic correlation. Accuracy with BayesCPR was affected by ignoring phenotypes of nongenotyped animals and maternal effect and by not accounting for parent average. Accuracy with BayesCDEBV was affected by approximations needed for deregression, not accounting for parent average, and sequential rather than simultaneous fitting of genomic and nongenomic information. Whereas BayesCDEBV presented a considerable bias, especially for maternal effect, ssGBLUP was unbiased for both effects. The computing time was 1 s for BLUP, 44 s for ssGBLUP, and over 2,000 s for BayesC. Greatest computational efficiency and accuracy of genomic prediction for a maternally affected trait was obtained when information from all nongenotyped but related individuals was included and phenotypes, pedigree, and genotypes were available and considered jointly. Increasing the gain in accuracy of genomic predictions obtained by ssGBLUP over BLUP may require an increase in the number of genotyped animals.
650 $aGANADERÍA
650 $aGANADO DE CARNE
650 $aMEJORAMIENTO GENÉTICO ANIMAL
650 $aMODELOS DE SIMULACIÓN
650 $aSELECCIÓN GENÓMICA
700 1 $aMISZTAL, I.
700 1 $aWANG, H.
700 1 $aAGUILAR, I.
700 1 $aTSURUTA, S.
700 1 $aBERTRAND, J.K.
773 $tJournal of Animal Science, 2013$gv.91, no.9, p.4090-4098.
Descargar
Esconder MarcPresentar Marc Completo |
|
Registro original : |
INIA Las Brujas (LB) |
|
|
Biblioteca
|
Identificación
|
Origen
|
Tipo / Formato
|
Clasificación
|
Cutter
|
Registro
|
Volumen
|
Estado
|
Volver
|
|
|
| Registros recuperados : 5 | |
| 1. |  | MACÍAS-RIOSECO, M.; CAFFARENA, D.; FRAGA, M.; SILVEIRA, C.S.; GIANNITTI, F.; CANTÓN, G.; HECKER, Y.P.; SUANES, A.; RIET-CORREA, F. Abortion outbreak caused by Campylobacter fetus subspecies venerealis and Neospora caninum in a bovine dairy herd. (Technical note). [Brote de abortos causado por Campylobacter fetus subespecie venerealis y Neospora caninum en un hato bovino lechero. (Nota de investigación)]. Revista Mexicana De Ciencias Pecuarias, 2019, Volume 10, Issue 4, 2019, Pages 1054-1063. OPEN ACCESS. Doi: 10.22319/rmcp.v10i4.5008 Article history: Recibido: 02 Agosto 2018. / Aceptado: 28 Agosto 2018.| Tipo: Artículos en Revistas Indexadas Internacionales | Circulación / Nivel : Internacional - -- |
| Biblioteca(s): INIA Las Brujas. |
|    |
| 2. | | DORSCH, M.; REGIDOR-CERRILLO, J.; ORTEGA-MORA, L.M.; SCIOLI, M.V.; MORRELL, E.L.; CANTÓN, G.J.; MOORE, D.P.; HECKER, Y.P. Microsatellite genotyping reveals extensive genetic diversity in bovine Neospora caninum from the humid Pampa region in Argentina. Parasitology Research, December 2020, Volume 119, Issue 12, Pages 4049-4059. Doi: https://doi-org/10.1007/s00436-020-06922-x Article history:Received: 12 August 2020 /Accepted: 5 October 2020| Tipo: Artículos en Revistas Indexadas Internacionales | Circulación / Nivel : Internacional - -- |
| Biblioteca(s): INIA La Estanzuela. |
|  |
| 4. | | GUAL, I.; GIANNITTI, F.; HECKER ,Y.P.; SHIVERS, J.; ENTROCASSI, A.C.; MORRELL ,E.L.; PARDINI, L.; FIORENTINO ,M.A.; RODRÍGUEZ FERMEPIN ,M.; UNZAGA ,J.M.; CANTÓN, G.J.; VENTURINI, M.C.; MOORE, D.P. First case report of Toxoplasma gondii-induced abortions and stillbirths in sheep in Argentina. Veterinary Parasitology: Regional Studies and Reports , v.12, p. 39-42, 2018. History article: Received 4 October 2017 // Received in revised form 8 January 2018// Accepted 9 January 2018 //Available online 11 January 2018.| Tipo: Artículos en Revistas Indexadas Internacionales | Circulación / Nivel : Internacional - -- |
| Biblioteca(s): INIA La Estanzuela. |
| |
| 5. | | HECKER, Y. P.; BURUCÚA, M. M.; FIORANI, F.; MALDONADO RIVERA, J. E.; CIRONE, K.M.; DORSCH, M.; CHEUQUEPÁN, F. A.; CAMPERO, L. M.; CANTÓN, G. J.; MARÍN, M. S.; ORTEGA-MORA, L. M.; MOORE, D. P. Reactivation and foetal infection in pregnant heifers infected with Neospora caninum live tachyzoites at prepubertal age. Vaccines, 2022, Volume 10, Issue 8, article 1175. OPEN ACCESS. doi: https://doi.org/10.3390/vaccines10081175 Article history: Received 5 July 2022; Revised 14 July 2022; Accepted 22 July 2022; Published 25 July 2022.
Corresponding author: Hecker, Y.P.; Instituto de Innovación para la Producción Agropecuaria y el Desarrollo Sostenible (IPADS),...| Tipo: Artículos en Revistas Indexadas Internacionales | Circulación / Nivel : Internacional - -- |
| Biblioteca(s): INIA Las Brujas. |
| |
| Registros recuperados : 5 | |
|
| No hay resultados para la expresión de búsqueda informada registros. |
|
|
