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 | Acceso al texto completo restringido a Biblioteca INIA Las Brujas. Por información adicional contacte bibliolb@inia.org.uy. |
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Registro completo
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Biblioteca (s) : |
INIA Las Brujas. |
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Fecha : |
21/01/2020 |
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Actualizado : |
21/01/2020 |
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Tipo de producción científica : |
Artículos en Revistas Indexadas Internacionales |
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Autor : |
DE CARVALHO NUNES, L.; STEGELMEIER, B. L.; COOK, D.; PFISTER, J. A.; GARDNER, D. R.; RIET-CORREA, F.; WEICH, K. D. |
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Afiliación : |
LOUISIANE DE CARVALHO NUNES, Department of Veterinary Science, Federal University of Espírito Santo, Alegre, Espírito Santo, Brazil; BRYAN L. STEGELMEIER, USDA-ARS Poisonous Plant Research Laboratory, USA; DANIEL COOK, USDA-ARS Poisonous Plant Research Laboratory, USA; JAMES A. PFISTER, USDA-ARS Poisonous Plant Research Laboratory, USA; DALE R. GARDNER, USDA-ARS Poisonous Plant Research Laboratory, USA; FRANKLIN RIET-CORREA AMARAL, INIA (Instituto Nacional de Investigación Agropecuaria), Uruguay; Veterinary Hospital, Center for Health and Rural Technology, Patos Campus, Federal University of Campina Grande, Brazil; KEVIN D. WELCH, USDA-ARS Poisonous Plant Research Laboratory, USA. |
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Título : |
Clinical and pathological comparison of Astragalus lentiginosus and Ipomoea carnea poisoning in goats. |
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Fecha de publicación : |
2019 |
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Fuente / Imprenta : |
Toxicon, 5 December, 2019, Volume 171, Pages 20-28. Doi: 10.1016/j.toxicon.2019.09.016 |
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ISSN : |
0041-0101 |
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DOI : |
10.1016/j.toxicon.2019.09.016 |
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Idioma : |
Inglés |
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Notas : |
Article history: Received 12 July 2019; Received in revised form 12 September 2019; Accepted 16 September 2019; Available online 19 September 2019. |
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Contenido : |
ABSTRACT.
The indolizidine alkaloid swainsonine, found in some Astragalus and Oxytropis (i.e., locoweed) species, is a potent cellular glycosidase inhibitor that often poisons livestock. Other toxic genera such as some Ipomoea species also contain swainsonine as well as calystegines which are similar polyhydroxy alkaloids. The toxicity of calystegines is poorly characterized; however, they are also potent glycoside inhibitors capable of intestinal and cellular glycoside dysfunction. The objective of this study was to directly compare A. lentiginosus and I. carnea poisoning in goats to better characterize the role of the calystegines. Three groups of four goats each were treated with ground alfalfa (control), I. carnea or A. lentiginosus to obtain daily doses of 0.0, 1.5, and 1.5 mg swainsonine/kg bw per day, respectively, for 45 days. Animals were observed daily and weekly body weights, serum enzyme activities, and serum swainsonine concentrations were determined. At day 45 all animals were euthanized and necropsied. Goats treated with A. lentiginosus and I. carnea developed clinical disease characterized by mild intention tremors and proprioceptive deficits. Goats treated with A. lentiginosus developed clinical disease sooner and with greater consistency. No differences in body weight, serum swainsonine concentrations and serum enzyme activity were observed between goats treated with A. lentiginosus and I. carnea. Additionally, there were no differences in the microscopic and histochemical studies of the visceral and neurologic lesions observed between goats treated with A. lentiginosus and I. carnea. These findings suggest that I. carnea-induced clinical signs and lesions are due to swainsonine and that calystegines contribute little or nothing to toxicity in goats in the presence of swainsonine.
© 2019 MenosABSTRACT.
The indolizidine alkaloid swainsonine, found in some Astragalus and Oxytropis (i.e., locoweed) species, is a potent cellular glycosidase inhibitor that often poisons livestock. Other toxic genera such as some Ipomoea species also contain swainsonine as well as calystegines which are similar polyhydroxy alkaloids. The toxicity of calystegines is poorly characterized; however, they are also potent glycoside inhibitors capable of intestinal and cellular glycoside dysfunction. The objective of this study was to directly compare A. lentiginosus and I. carnea poisoning in goats to better characterize the role of the calystegines. Three groups of four goats each were treated with ground alfalfa (control), I. carnea or A. lentiginosus to obtain daily doses of 0.0, 1.5, and 1.5 mg swainsonine/kg bw per day, respectively, for 45 days. Animals were observed daily and weekly body weights, serum enzyme activities, and serum swainsonine concentrations were determined. At day 45 all animals were euthanized and necropsied. Goats treated with A. lentiginosus and I. carnea developed clinical disease characterized by mild intention tremors and proprioceptive deficits. Goats treated with A. lentiginosus developed clinical disease sooner and with greater consistency. No differences in body weight, serum swainsonine concentrations and serum enzyme activity were observed between goats treated with A. lentiginosus and I. carnea. Additionally, there were no differences in the microscopic a... Presentar Todo |
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Palabras claves : |
Astragalus; Calystegines; Ipomoea; Locoweed; PLATAFORMA SALUD ANIMAL; Swainsonine. |
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Asunto categoría : |
A50 Investigación agraria |
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Marc : |
LEADER 02878naa a2200301 a 4500
001 1060655
005 2020-01-21
008 2019 bl uuuu u00u1 u #d
022 $a0041-0101
024 7 $a10.1016/j.toxicon.2019.09.016$2DOI
100 1 $aDE CARVALHO NUNES, L.
245 $aClinical and pathological comparison of Astragalus lentiginosus and Ipomoea carnea poisoning in goats.$h[electronic resource]
260 $c2019
500 $aArticle history: Received 12 July 2019; Received in revised form 12 September 2019; Accepted 16 September 2019; Available online 19 September 2019.
520 $aABSTRACT. The indolizidine alkaloid swainsonine, found in some Astragalus and Oxytropis (i.e., locoweed) species, is a potent cellular glycosidase inhibitor that often poisons livestock. Other toxic genera such as some Ipomoea species also contain swainsonine as well as calystegines which are similar polyhydroxy alkaloids. The toxicity of calystegines is poorly characterized; however, they are also potent glycoside inhibitors capable of intestinal and cellular glycoside dysfunction. The objective of this study was to directly compare A. lentiginosus and I. carnea poisoning in goats to better characterize the role of the calystegines. Three groups of four goats each were treated with ground alfalfa (control), I. carnea or A. lentiginosus to obtain daily doses of 0.0, 1.5, and 1.5 mg swainsonine/kg bw per day, respectively, for 45 days. Animals were observed daily and weekly body weights, serum enzyme activities, and serum swainsonine concentrations were determined. At day 45 all animals were euthanized and necropsied. Goats treated with A. lentiginosus and I. carnea developed clinical disease characterized by mild intention tremors and proprioceptive deficits. Goats treated with A. lentiginosus developed clinical disease sooner and with greater consistency. No differences in body weight, serum swainsonine concentrations and serum enzyme activity were observed between goats treated with A. lentiginosus and I. carnea. Additionally, there were no differences in the microscopic and histochemical studies of the visceral and neurologic lesions observed between goats treated with A. lentiginosus and I. carnea. These findings suggest that I. carnea-induced clinical signs and lesions are due to swainsonine and that calystegines contribute little or nothing to toxicity in goats in the presence of swainsonine. © 2019
653 $aAstragalus
653 $aCalystegines
653 $aIpomoea
653 $aLocoweed
653 $aPLATAFORMA SALUD ANIMAL
653 $aSwainsonine
700 1 $aSTEGELMEIER, B. L.
700 1 $aCOOK, D.
700 1 $aPFISTER, J. A.
700 1 $aGARDNER, D. R.
700 1 $aRIET-CORREA, F.
700 1 $aWEICH, K. D.
773 $tToxicon, 5 December, 2019, Volume 171, Pages 20-28. Doi: 10.1016/j.toxicon.2019.09.016
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Registro original : |
INIA Las Brujas (LB) |
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Registro completo
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Biblioteca (s) : |
INIA Treinta y Tres. |
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Fecha actual : |
26/09/2014 |
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Actualizado : |
11/02/2019 |
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Tipo de producción científica : |
Artículos en Revistas Indexadas Internacionales |
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Circulación / Nivel : |
C - 0 |
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Autor : |
ALONSO, R.; LUPO, S.; MARTINEZ, S.; TISCORNIA, S.; BETTUCCI, L. |
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Afiliación : |
SEBASTIAN MARTINEZ KOPP, INIA (Instituto Nacional de Investigación Agropecuaria), Uruguay. |
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Título : |
Development of sprouted stumps of Eucalyptus globulus and E. maidenii in Uruguay. |
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Fecha de publicación : |
2012 |
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Fuente / Imprenta : |
Australian Forestry. 2012. v.75, no.2, p. 130-134. |
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DOI : |
10.1080/00049158.2012.10676394 |
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Idioma : |
Inglés |
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Notas : |
Article manuscript receibed 24 August 2011. |
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Contenido : |
Summary
Eucalyptus globulus ssp. globulus Labill. and E. globulus ssp. maidenii (Mueller) Kirkpatrick are two of the main plantation species used in Uruguay. When felled, stumps of these species have the ability to produce new growth via dormant buds situated beneath the bark. The aim of this study was to evaluate the survival of coppice arising from the dormant buds and to determine if pathogenic wood-rooting fungi colonised the stumps and reduced sprouting. The development of coppice from stumps of trees felled monthly over a six-month period was evaluated five times over about 18 months in each instance. Coppice of E. maidenii remained alive longer than did that of E. globulus. At the stump surface more than 40% of the bark of E. globulus was detached; this could be associated with the death of coppice and low survival of stumps. Consequently, new plantations are being established by planting between rows of stumps, instead of trying to manage the stump coppice. Several wood-rotting fungi colonising stump surfaces were identified, but no pathogenic species were associated with the death of coppice or stumps. |
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Palabras claves : |
BANK; COPPICE; INJURIES; MORTALITY; PATHOGENS; PLANTING; REGENERATION; WOOD DESTROYING FUNGI. |
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Thesagro : |
AGENTES PATOGENOS; BJERKANDERO ADUSTA; EUCALIPTUS; HONGOS DE LA MADERA; HYMENOMYCETES; PYCNOPORUS SANGUINEUS; QUAMBALARIA EUCALYPTI; SCHIZOPORA PARADOXA. |
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Asunto categoría : |
K70 Daños al bosque y protección forestal |
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Marc : |
LEADER 02217naa a2200385 a 4500
001 1050563
005 2019-02-11
008 2012 bl uuuu u00u1 u #d
024 7 $a10.1080/00049158.2012.10676394$2DOI
100 1 $aALONSO, R.
245 $aDevelopment of sprouted stumps of Eucalyptus globulus and E. maidenii in Uruguay.$h[electronic resource]
260 $c2012
500 $aArticle manuscript receibed 24 August 2011.
520 $aSummary Eucalyptus globulus ssp. globulus Labill. and E. globulus ssp. maidenii (Mueller) Kirkpatrick are two of the main plantation species used in Uruguay. When felled, stumps of these species have the ability to produce new growth via dormant buds situated beneath the bark. The aim of this study was to evaluate the survival of coppice arising from the dormant buds and to determine if pathogenic wood-rooting fungi colonised the stumps and reduced sprouting. The development of coppice from stumps of trees felled monthly over a six-month period was evaluated five times over about 18 months in each instance. Coppice of E. maidenii remained alive longer than did that of E. globulus. At the stump surface more than 40% of the bark of E. globulus was detached; this could be associated with the death of coppice and low survival of stumps. Consequently, new plantations are being established by planting between rows of stumps, instead of trying to manage the stump coppice. Several wood-rotting fungi colonising stump surfaces were identified, but no pathogenic species were associated with the death of coppice or stumps.
650 $aAGENTES PATOGENOS
650 $aBJERKANDERO ADUSTA
650 $aEUCALIPTUS
650 $aHONGOS DE LA MADERA
650 $aHYMENOMYCETES
650 $aPYCNOPORUS SANGUINEUS
650 $aQUAMBALARIA EUCALYPTI
650 $aSCHIZOPORA PARADOXA
653 $aBANK
653 $aCOPPICE
653 $aINJURIES
653 $aMORTALITY
653 $aPATHOGENS
653 $aPLANTING
653 $aREGENERATION
653 $aWOOD DESTROYING FUNGI
700 1 $aLUPO, S.
700 1 $aMARTINEZ, S.
700 1 $aTISCORNIA, S.
700 1 $aBETTUCCI, L.
773 $tAustralian Forestry. 2012.$gv.75, no.2, p. 130-134.
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