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 | Acceso al texto completo restringido a Biblioteca INIA La Estanzuela. Por información adicional contacte bib_le@inia.org.uy. |
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Registro completo
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Biblioteca (s) : |
INIA La Estanzuela. |
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Fecha : |
31/05/2022 |
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Actualizado : |
02/12/2022 |
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Tipo de producción científica : |
Artículos en Revistas Indexadas Internacionales |
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Autor : |
COSTA, M.; SARAVIA, A.; UBIOS, D.; LORES, L.; DA COSTA, V.; FESTARI, M.F.; LANDEIRA, M.; RODRÍGUEZ-ZRAQUIA, S.A.; BANCHERO, G.; FREIRE, T. |
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Afiliación : |
MONIQUE COSTA, Laboratorio de Inmunomodulación y Desarrollo de Vacunas, Departamento de Inmunobiología, Facultad de Medicina, Universidad de La República, Montevideo, Uruguay.; ANDERSON SARAVIA DE MELO, INIA (Instituto Nacional de Investigación Agropecuaria), Uruguay; DIEGO UBIOS, INIA (Instituto Nacional de Investigación Agropecuaria), Uruguay.; PABLO LORES, Laboratorio de Inmunomodulación y Desarrollo de Vacunas, Departamento de Inmunobiología, Facultad de Medicina, Universidad de La República, Montevideo, Uruguay.; VALERIA DA COSTA, Laboratorio de Inmunomodulación y Desarrollo de Vacunas, Departamento de Inmunobiología, Facultad de Medicina, Universidad de La República, Montevideo, Uruguay.; MARÍA FLORENCIA FESTARI, Laboratorio de Inmunomodulación y Desarrollo de Vacunas, Departamento de Inmunobiología, Facultad de Medicina, Universidad de La República, Montevideo, Uruguay.; MERCEDES LANDEIRA, Laboratorio de Inmunomodulación y Desarrollo de Vacunas, Departamento de Inmunobiología, Facultad de Medicina, Universidad de La República, Montevideo, Uruguay; SANTIAGO A. RODRÍGUEZ-ZRAQUIA, Laboratorio de Inmunomodulación y Desarrollo de Vacunas, Departamento de Inmunobiología, Facultad de Medicina, Universidad de La República, Montevideo, Uruguay.; GEORGGET ELIZABETH BANCHERO HUNZIKER, INIA (Instituto Nacional de Investigación Agropecuaria), Uruguay; TERESA FREIRE, Laboratorio de Inmunomodulación y Desarrollo de Vacunas, Departamento de Inmunobiología, Facultad de Medicina, Universidad de La República, Montevideo, Uruguay. |
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Título : |
Liver function markers and haematological dynamics during acute and chronic phases of experimental Fasciola hepatica infection in cattle treated with triclabendazole. |
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Fecha de publicación : |
2022 |
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Fuente / Imprenta : |
Experimental Parasitology, July 2022, Volume 238, e108285. doi://doi.org/10.1016/j.exppara.2022.108285 |
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ISSN : |
0014-4894 |
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DOI : |
10.1016/j.exppara.2022.108285 |
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Idioma : |
Inglés |
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Notas : |
Article history: Received 13 September 2021; Revised 24 May 2022; Accepted 27 May 2022; Available online 30 May 2022; Published July 2022. -- Corresponding author : Freire, T.; Facultad de Medicina, Departamento de Inmunobiología. Gral. Flores 2125, Montevideo, Uruguay; email:tfreire@fmed.edu.uy -- |
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Contenido : |
Abstract:
Fasciola hepatica, a worldwide-distributed liver fluke, is one of the causative agents of fasciolosis, a zoonotic disease that affects livestock and humans. In livestock, fasciolosis causes huge economic losses worldwide, reducing animal fertility, milk production, weight gain and condemnation of livers. In spite of the availability of drugs, such as triclabendazole (TCZ), for the treatment of fasciolosis, they do not necessarily prevent liver damage or parasite reinfection and can eventually increase parasite resistance. The aim of this research was to relate the hepatic function, haematological parameters, leukocyte counts in circulation and parasite egg shedding during F. hepatica acute and chronic phases of infection in cattle as well as to determine how these parameters change with TCZ-treatment of chronically infected cattle. Our results show that increased levels of serum aspartate aminotransferase (AST) and gamma glutamyltransferase (GGT) were detected in early stages of the experimental infection. Moreover, high circulating eosinophil count and plateletcrit levels were correlated with fluke number in livers from infected cattle. On the other hand, although TCZ-treatment in the chronic phase of infection reduced parasite burden and damage in the liver, it was not able to completely avoid them. In conclusion, our work sheds light into the physiopathological mechanisms induced during fluke infection in cattle, revealing the complexity of the host response to the infection, together with the effects of TCZ-treatment in chronically infected animals. © 2022 MenosAbstract:
Fasciola hepatica, a worldwide-distributed liver fluke, is one of the causative agents of fasciolosis, a zoonotic disease that affects livestock and humans. In livestock, fasciolosis causes huge economic losses worldwide, reducing animal fertility, milk production, weight gain and condemnation of livers. In spite of the availability of drugs, such as triclabendazole (TCZ), for the treatment of fasciolosis, they do not necessarily prevent liver damage or parasite reinfection and can eventually increase parasite resistance. The aim of this research was to relate the hepatic function, haematological parameters, leukocyte counts in circulation and parasite egg shedding during F. hepatica acute and chronic phases of infection in cattle as well as to determine how these parameters change with TCZ-treatment of chronically infected cattle. Our results show that increased levels of serum aspartate aminotransferase (AST) and gamma glutamyltransferase (GGT) were detected in early stages of the experimental infection. Moreover, high circulating eosinophil count and plateletcrit levels were correlated with fluke number in livers from infected cattle. On the other hand, although TCZ-treatment in the chronic phase of infection reduced parasite burden and damage in the liver, it was not able to completely avoid them. In conclusion, our work sheds light into the physiopathological mechanisms induced during fluke infection in cattle, revealing the complexity of the host response to ... Presentar Todo |
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Palabras claves : |
Fasciola hepatica; Fasciolosis; Fluke; LIVER; PLATAFORMA DE SALUD ANIMAL; Triclabendazole. |
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Asunto categoría : |
L73 Enfermedades de los animales |
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Marc : |
LEADER 02950naa a2200337 a 4500
001 1063184
005 2022-12-02
008 2022 bl uuuu u00u1 u #d
022 $a0014-4894
024 7 $a10.1016/j.exppara.2022.108285$2DOI
100 1 $aCOSTA, M.
245 $aLiver function markers and haematological dynamics during acute and chronic phases of experimental Fasciola hepatica infection in cattle treated with triclabendazole.$h[electronic resource]
260 $c2022
500 $aArticle history: Received 13 September 2021; Revised 24 May 2022; Accepted 27 May 2022; Available online 30 May 2022; Published July 2022. -- Corresponding author : Freire, T.; Facultad de Medicina, Departamento de Inmunobiología. Gral. Flores 2125, Montevideo, Uruguay; email:tfreire@fmed.edu.uy --
520 $aAbstract: Fasciola hepatica, a worldwide-distributed liver fluke, is one of the causative agents of fasciolosis, a zoonotic disease that affects livestock and humans. In livestock, fasciolosis causes huge economic losses worldwide, reducing animal fertility, milk production, weight gain and condemnation of livers. In spite of the availability of drugs, such as triclabendazole (TCZ), for the treatment of fasciolosis, they do not necessarily prevent liver damage or parasite reinfection and can eventually increase parasite resistance. The aim of this research was to relate the hepatic function, haematological parameters, leukocyte counts in circulation and parasite egg shedding during F. hepatica acute and chronic phases of infection in cattle as well as to determine how these parameters change with TCZ-treatment of chronically infected cattle. Our results show that increased levels of serum aspartate aminotransferase (AST) and gamma glutamyltransferase (GGT) were detected in early stages of the experimental infection. Moreover, high circulating eosinophil count and plateletcrit levels were correlated with fluke number in livers from infected cattle. On the other hand, although TCZ-treatment in the chronic phase of infection reduced parasite burden and damage in the liver, it was not able to completely avoid them. In conclusion, our work sheds light into the physiopathological mechanisms induced during fluke infection in cattle, revealing the complexity of the host response to the infection, together with the effects of TCZ-treatment in chronically infected animals. © 2022
653 $aFasciola hepatica
653 $aFasciolosis
653 $aFluke
653 $aLIVER
653 $aPLATAFORMA DE SALUD ANIMAL
653 $aTriclabendazole
700 1 $aSARAVIA, A.
700 1 $aUBIOS, D.
700 1 $aLORES, L.
700 1 $aDA COSTA, V.
700 1 $aFESTARI, M.F.
700 1 $aLANDEIRA, M.
700 1 $aRODRÍGUEZ-ZRAQUIA, S.A.
700 1 $aBANCHERO, G.
700 1 $aFREIRE, T.
773 $tExperimental Parasitology, July 2022, Volume 238, e108285. doi://doi.org/10.1016/j.exppara.2022.108285
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INIA La Estanzuela (LE) |
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| Acceso al texto completo restringido a Biblioteca INIA La Estanzuela. Por información adicional contacte bib_le@inia.org.uy. |
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Registro completo
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|
Biblioteca (s) : |
INIA La Estanzuela. |
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Fecha actual : |
07/04/2021 |
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Actualizado : |
07/04/2021 |
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Tipo de producción científica : |
Artículos en Revistas Indexadas Internacionales |
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Circulación / Nivel : |
Internacional - -- |
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Autor : |
BUSTAMANTE-SILVEIRA, M.; SIRI-PRIETO, G.; CARRASCO-LETELIER, L. |
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Afiliación : |
MAURICIO BUSTAMANTE-SILVEIRA, Estación Experimental Mario Cassinoni (EEMAC), Facultad de Agronomía, Universidad de la República, Ruta 3 km 363, Paysandú, Uruguay.; GUILLERMO SIRI-PRIETO, stación Experimental Mario Cassinoni (EEMAC), Facultad de Agronomía, Universidad de la República, Ruta 3 km 363, Paysandú, Uruguay; LEONIDAS CARRASCO-LETELIER, INIA (Instituto Nacional de Investigación Agropecuaria), Uruguay. |
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Título : |
Water footprints of bioethanol cropping systems in Uruguay, |
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Fecha de publicación : |
2021 |
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Fuente / Imprenta : |
Agricultural Water Management, 30 June 2021, Volume 252, Article 106870. Doi: https://doi.org/10.1016/j.agwat.2021.106870 |
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DOI : |
10.1016/j.agwat.2021.106870 |
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Idioma : |
Inglés |
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Notas : |
Article history: Received 4 June 2020/ Revised 10 March 2021/ Accepted 13 March 2021/ Available online 5 April 2021. Corresponding author:
E-mail address: bustamantefagro@gmail.com (M. Bustamante-Silveira). |
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Contenido : |
ABSTRACT: Bioenergy is the most widely used type of renewable energy. However, an assessment of water consumption and
pollution is necessary to determine the water demand of this energy source. The Uruguayan public policy to decarbonize energy sources highlighted the use of bioenergy. In this regard, we analyzed the water footprint (WF) of four bioethanol cropping systems: (1) maize-wheat-sorghum rotation without harvested crop residues (MWS), (2) maize-wheat-sorghum rotation with harvested crop residues (MWS-R), (3) continuous sweet sorghum (Ss), and (4) switchgrass (Sw). In order to assess the WF of bioethanol production, green (WFgreen) and gray
(WFgray) components of crop production were calculated by considering the different volumes of water involved
in evaporation, rainfall, and fertilizer pollution. Annual cropping systems (i.e., MWS, MWS-R, Ss) had the largest
WFs (23.1?30.9 m3 L? 1 ethanol). Switchgrass had the lowest values per hectare and per liter of ethanol
(12,735 m3 (ha yr)? 1 and 3.8 m3 L? 1 ethanol, respectively). The volume required to assimilate phosphorous (P) and
nitrogen (N) fertilizers played a significant role in bioethanol cropping systems. In annual systems, WFgray was
the main fraction (87%) of total WF (WFT). Averaged across all cropping systems, WFgray related to P was 13
times larger than WFgray related to N. |
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Palabras claves : |
BIOENERGY; GRAY WATER; GREEN WATER; HUELLA HIDRICA; INTESIFICATION; SOIL EROSION. |
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Thesagro : |
ENERGIA RENOVABLE. |
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Asunto categoría : |
-- |
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Marc : |
LEADER 02354naa a2200253 a 4500
001 1061959
005 2021-04-07
008 2021 bl uuuu u00u1 u #d
024 7 $a10.1016/j.agwat.2021.106870$2DOI
100 1 $aBUSTAMANTE-SILVEIRA, M.
245 $aWater footprints of bioethanol cropping systems in Uruguay,$h[electronic resource]
260 $c2021
500 $aArticle history: Received 4 June 2020/ Revised 10 March 2021/ Accepted 13 March 2021/ Available online 5 April 2021. Corresponding author: E-mail address: bustamantefagro@gmail.com (M. Bustamante-Silveira).
520 $aABSTRACT: Bioenergy is the most widely used type of renewable energy. However, an assessment of water consumption and pollution is necessary to determine the water demand of this energy source. The Uruguayan public policy to decarbonize energy sources highlighted the use of bioenergy. In this regard, we analyzed the water footprint (WF) of four bioethanol cropping systems: (1) maize-wheat-sorghum rotation without harvested crop residues (MWS), (2) maize-wheat-sorghum rotation with harvested crop residues (MWS-R), (3) continuous sweet sorghum (Ss), and (4) switchgrass (Sw). In order to assess the WF of bioethanol production, green (WFgreen) and gray (WFgray) components of crop production were calculated by considering the different volumes of water involved in evaporation, rainfall, and fertilizer pollution. Annual cropping systems (i.e., MWS, MWS-R, Ss) had the largest WFs (23.1?30.9 m3 L? 1 ethanol). Switchgrass had the lowest values per hectare and per liter of ethanol (12,735 m3 (ha yr)? 1 and 3.8 m3 L? 1 ethanol, respectively). The volume required to assimilate phosphorous (P) and nitrogen (N) fertilizers played a significant role in bioethanol cropping systems. In annual systems, WFgray was the main fraction (87%) of total WF (WFT). Averaged across all cropping systems, WFgray related to P was 13 times larger than WFgray related to N.
650 $aENERGIA RENOVABLE
653 $aBIOENERGY
653 $aGRAY WATER
653 $aGREEN WATER
653 $aHUELLA HIDRICA
653 $aINTESIFICATION
653 $aSOIL EROSION
700 1 $aSIRI-PRIETO, G.
700 1 $aCARRASCO-LETELIER, L.
773 $tAgricultural Water Management, 30 June 2021, Volume 252, Article 106870. Doi: https://doi.org/10.1016/j.agwat.2021.106870
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