| |
|
|
 | Acceso al texto completo restringido a Biblioteca INIA Las Brujas. Por información adicional contacte bibliolb@inia.org.uy. |
|
Registro completo
|
|
Biblioteca (s) : |
INIA Las Brujas. |
|
Fecha : |
21/10/2024 |
|
Actualizado : |
21/10/2024 |
|
Tipo de producción científica : |
Artículos en Revistas Indexadas Internacionales |
|
Autor : |
LOZANO, J.; FABIUS, S.; FERNÁNDEZ-CIGANDA, S.; URBANAVICIUS, J.; PICCINI, C.; SCORZA, C.; ZUNINO, Z. |
|
Afiliación : |
J. LOZANO, Department of Microbiology, Instituto de Investigaciones Biológicas Clemente Estable, Montevideo, Uruguay; S. FABIUS, Department of Experimental Neuropharmacology, Instituto de Investigaciones Biológicas Clemente Estable, Montevideo, Uruguay; SOFÍA FERNÁNDEZ-CIGANDA, INIA (Instituto Nacional de Investigación Agropecuaria), Uruguay; Department of Microbiology, Instituto de Investigaciones Biológicas Clemente Estable, Montevideo, Uruguay; J. URBANAVICIUS, Department of Experimental Neuropharmacology, Instituto de Investigaciones Biológicas Clemente Estable, Montevideo, Uruguay; C. PICCINI, Department of Microbiology, Instituto de Investigaciones Biológicas Clemente Estable, Montevideo, Uruguay; C. SCORZA, Department of Experimental Neuropharmacology, Instituto de Investigaciones Biológicas Clemente Estable, Montevideo, Uruguay; P. ZUNINO, Department of Microbiology, Instituto de Investigaciones Biológicas Clemente Estable, Montevideo, Uruguay. |
|
Título : |
Beneficial effect of GABA-producing Lactiplantibacillus strain LPB145 isolated from cheese starters evaluated in anxiety- and depression-like
behaviours in rats. |
|
Complemento del título : |
Research article. |
|
Fecha de publicación : |
2024 |
|
Fuente / Imprenta : |
Beneficial Microbes, 2024, Volume 15, Issue 5, Pages 465-479. https://doi.org/10.1163/18762891-bja00024 |
|
ISSN : |
1876-2891 (online) |
|
DOI : |
10.1163/18762891-bja00024 |
|
Idioma : |
Inglés |
|
Notas : |
Article history: Received 21 October 2023, Accepted 19 June 2024, Published online 4 July 2024. -- Correspondence: Zunino, P.; Department of Microbiology, Instituto de Investigaciones Biológicas Clemente Estable, Montevideo, Uruguay; email:pmzunino@gmail.com -- Published with license by Koninklijke Brill BV. |
|
Contenido : |
ABSTRACT.- In a previous study, we reported the in vitro potential probiotic and gamma-aminobutyric acid (GABA) production, of several strains from a collection of Lactiplantibacillus (Lpb) strains within the community of natural whey starters from the artisanal cheese industry. GABA is a non-protein amino acid widely distributed in nature and produced in animals, plants, and microorganisms. However, the best known role of GABA is its function as the major inhibitory neurotransmitter of the central nervous system. Preclinical and clinical evidence suggests that the GABAergic system has a relevant role in mental health disorders, such as anxiety and major depression. The modulation of the GABAergic system has been suggested as a potential strategy for treatment, one such mechanism of modulation is the influence of the microbiota-gut-brain axis through probiotic treatments. The present study was designed to investigate the in vivo probiotic potential of LPB145, a Lactiplantibacillus strain previously characterised as a GABA-producing potentially probiotic strain. Therefore, we evaluated the behavioural effects of chronic oral administration of LPB145 on rats' anxiety- and depression-like behaviours, using the elevated plus maze, open field, and the forced swimming test. The impact of LPB145 strain treatment on the gut microbiota structure and diversity was assessed to discern a possible mechanism of action of the LPB145 treatment through the microbiota-gut-brain axis. Our results showed that LPB145 administration induced an antidepressive-like behaviour without changes in locomotor activity. In contrast, the treatment did not modify the experimental anxiety. The structure and diversity of the intestinal microbiota remained unaffected by the treatment when compared to the control. However, specific clades that could be implicated in the behavioural changes did show differences in their relative abundance. These findings provide evidence regarding the potential of probiotic strains isolated from alimentary sources, to modulate the microbiota-gut-brain axis and positively impact mental health. © J. LOZANO et al., 2024. MenosABSTRACT.- In a previous study, we reported the in vitro potential probiotic and gamma-aminobutyric acid (GABA) production, of several strains from a collection of Lactiplantibacillus (Lpb) strains within the community of natural whey starters from the artisanal cheese industry. GABA is a non-protein amino acid widely distributed in nature and produced in animals, plants, and microorganisms. However, the best known role of GABA is its function as the major inhibitory neurotransmitter of the central nervous system. Preclinical and clinical evidence suggests that the GABAergic system has a relevant role in mental health disorders, such as anxiety and major depression. The modulation of the GABAergic system has been suggested as a potential strategy for treatment, one such mechanism of modulation is the influence of the microbiota-gut-brain axis through probiotic treatments. The present study was designed to investigate the in vivo probiotic potential of LPB145, a Lactiplantibacillus strain previously characterised as a GABA-producing potentially probiotic strain. Therefore, we evaluated the behavioural effects of chronic oral administration of LPB145 on rats' anxiety- and depression-like behaviours, using the elevated plus maze, open field, and the forced swimming test. The impact of LPB145 strain treatment on the gut microbiota structure and diversity was assessed to discern a possible mechanism of action of the LPB145 treatment through the microbiota-gut-brain axis. Our resu... Presentar Todo |
|
Palabras claves : |
Depression; Gamma-aminobutyric acid; Intestinal microbiota; MGB axis; Natural whey starter; PLATAFORMA DE INVESTIGACIÓN EN SALUD ANIMAL - INIA; Probiotic; Rats. |
|
Asunto categoría : |
A50 Investigación agraria |
|
Marc : |
LEADER 03533naa a2200325 a 4500
001 1064885
005 2024-10-21
008 2024 bl uuuu u00u1 u #d
022 $a1876-2891 (online)
024 7 $a10.1163/18762891-bja00024$2DOI
100 1 $aLOZANO, J.
245 $aBeneficial effect of GABA-producing Lactiplantibacillus strain LPB145 isolated from cheese starters evaluated in anxiety- and depression-like behaviours in rats.$h[electronic resource]
260 $c2024
500 $aArticle history: Received 21 October 2023, Accepted 19 June 2024, Published online 4 July 2024. -- Correspondence: Zunino, P.; Department of Microbiology, Instituto de Investigaciones Biológicas Clemente Estable, Montevideo, Uruguay; email:pmzunino@gmail.com -- Published with license by Koninklijke Brill BV.
520 $aABSTRACT.- In a previous study, we reported the in vitro potential probiotic and gamma-aminobutyric acid (GABA) production, of several strains from a collection of Lactiplantibacillus (Lpb) strains within the community of natural whey starters from the artisanal cheese industry. GABA is a non-protein amino acid widely distributed in nature and produced in animals, plants, and microorganisms. However, the best known role of GABA is its function as the major inhibitory neurotransmitter of the central nervous system. Preclinical and clinical evidence suggests that the GABAergic system has a relevant role in mental health disorders, such as anxiety and major depression. The modulation of the GABAergic system has been suggested as a potential strategy for treatment, one such mechanism of modulation is the influence of the microbiota-gut-brain axis through probiotic treatments. The present study was designed to investigate the in vivo probiotic potential of LPB145, a Lactiplantibacillus strain previously characterised as a GABA-producing potentially probiotic strain. Therefore, we evaluated the behavioural effects of chronic oral administration of LPB145 on rats' anxiety- and depression-like behaviours, using the elevated plus maze, open field, and the forced swimming test. The impact of LPB145 strain treatment on the gut microbiota structure and diversity was assessed to discern a possible mechanism of action of the LPB145 treatment through the microbiota-gut-brain axis. Our results showed that LPB145 administration induced an antidepressive-like behaviour without changes in locomotor activity. In contrast, the treatment did not modify the experimental anxiety. The structure and diversity of the intestinal microbiota remained unaffected by the treatment when compared to the control. However, specific clades that could be implicated in the behavioural changes did show differences in their relative abundance. These findings provide evidence regarding the potential of probiotic strains isolated from alimentary sources, to modulate the microbiota-gut-brain axis and positively impact mental health. © J. LOZANO et al., 2024.
653 $aDepression
653 $aGamma-aminobutyric acid
653 $aIntestinal microbiota
653 $aMGB axis
653 $aNatural whey starter
653 $aPLATAFORMA DE INVESTIGACIÓN EN SALUD ANIMAL - INIA
653 $aProbiotic
653 $aRats
700 1 $aFABIUS, S.
700 1 $aFERNÁNDEZ-CIGANDA, S.
700 1 $aURBANAVICIUS, J.
700 1 $aPICCINI, C.
700 1 $aSCORZA, C.
700 1 $aZUNINO, Z.
773 $tBeneficial Microbes, 2024, Volume 15, Issue 5, Pages 465-479. https://doi.org/10.1163/18762891-bja00024
Descargar
Esconder MarcPresentar Marc Completo |
|
Registro original : |
INIA Las Brujas (LB) |
|
|
Biblioteca
|
Identificación
|
Origen
|
Tipo / Formato
|
Clasificación
|
Cutter
|
Registro
|
Volumen
|
Estado
|
Volver
|
|
|
| Acceso al texto completo restringido a Biblioteca INIA Tacuarembó. Por información adicional contacte bibliotb@tb.inia.org.uy. |
|
Registro completo
|
|
Biblioteca (s) : |
INIA Tacuarembó. |
|
Fecha actual : |
29/11/2018 |
|
Actualizado : |
04/02/2020 |
|
Tipo de producción científica : |
Artículos en Revistas Indexadas Internacionales |
|
Circulación / Nivel : |
Internacional - -- |
|
Autor : |
RESQUÍN, F.; NAVARRO-CERRILLO, R.M.; RACHID, C.; HIRIGOYEN, A.; CARRASCO-LETELIER, L.; DUQUE-LAZO, J. |
|
Afiliación : |
JOSE FERNANDO RESQUIN PEREZ, INIA (Instituto Nacional de Investigación Agropecuaria), Uruguay; RAFAEL M. NAVARRO-CERRILLO., E.T.S.I.A.M. Department of Forestry, School of Agriculture and Forestry, University of Córdoba, Campus de Rabanales, Córdoba, Spain.; ANA CECILIA RACHID CASNATI, INIA (Instituto Nacional de Investigación Agropecuaria), Uruguay; ANDRES EDUARDO HIRIGOYEN DOMINGUEZ, INIA (Instituto Nacional de Investigación Agropecuaria), Uruguay; LEONIDAS CARRASCO-LETELIER, INIA (Instituto Nacional de Investigación Agropecuaria), Uruguay; JOAQUÍN DUQUE-LAZO, E.T.S.I.A.M. Department of Forestry, School of Agriculture and Forestry, University of Córdoba, Campus de Rabanales, Córdoba, Spain. |
|
Título : |
Allometry, Growth and Survival of Three Eucalyptus Species (Eucalyptus benthamii Maiden and Cambage, E. dunnii Maiden and E. grandis Hill ex Maiden) in High-Density Plantations in Uruguay. |
|
Fecha de publicación : |
2018 |
|
Fuente / Imprenta : |
Forests 2018. |
|
DOI : |
10.3390/f9120745 |
|
Idioma : |
Inglés |
|
Notas : |
Article history: Received: 18 October 2018; Accepted: 13 November 2018; Published: 29 November 2018. Author Contributions: F.R., C.R.-C. and L.C.-L. planned and designed the research. F.R. and C.R.-C. conducted fieldwork and performed experiments. R.M.N.-C., A.H. and J.D.-L. contributed to data elaboration and analysis. F.R., R.M.N.-C. and L.C.-L. wrote the manuscript, with contributions by all authors. // Funding: This study was funded by the National Research Institute of Agriculture Research (INIA) and National Agency for Research and Innovation (ANII) through the grant FSE 1 2011 15615 (Evaluación productiva y ambiental de plantaciones forestales para la generación de Bioenergía). Acknowledgments: The authors thank the INIA, ANII and Forestal Oriental company for its collaboration with the field experiments and plantations |
|
Contenido : |
This study presents a yield model for aboveground biomass production from three species the Eucalyptus in northern and western regions of Uruguay, based on sampling records from intensive crop plantations. High-density eucalyptus plantations represent a forestry alternative for the production of forest biomass. This work assessed the survival and growth of three eucalyptus species (Eucalyptus benthamii Maiden & Cambage, E. dunnii Maiden and E. grandis Hill ex Maiden) planted at densities of 2220, 3330, 4440 and 6660 trees ha-1, for a period of 57 months in northern (Tacuarembó) and western (Paysandú) regions of Uruguay. Linear and logarithmic equations of individual volume were fitted by site and species. The survival of E. grandis, E. benthamii and E. dunnii was not related to planting density, and the highest mortality values occurred in Tacuarembó. The effects of competition among trees were more evident at the highest planting density for E. grandis. In all species, the reduction in diameter was more marked than that of height, as planting density increased. Tree volume showed the same trend, and this was higher with higher planting densities. At Tacuarembó, the volume was the highest with E. benthamii at 6660 trees ha-1 (416.4 m3 ha-1), and, at Paysandú, the highest production was obtained with E. grandis (370.7 m3 ha-1) and with the densities of 4440 and 6660 trees ha-1 (305.9 and 315.3 m3 ha-1, respectively). With all species and planting densities, there was an increase in the accumulated volume during the 57-month study period; however, growth curves indicate that the maximum production per unit time and, therefore,
the optimum harvest time occurred at 48 months. In this work, it has been shown that the use of intensive short-rotation plantations of eucalyptus for the production of biomass in Uruguay is suitable in soils prioritized for forestry. MenosThis study presents a yield model for aboveground biomass production from three species the Eucalyptus in northern and western regions of Uruguay, based on sampling records from intensive crop plantations. High-density eucalyptus plantations represent a forestry alternative for the production of forest biomass. This work assessed the survival and growth of three eucalyptus species (Eucalyptus benthamii Maiden & Cambage, E. dunnii Maiden and E. grandis Hill ex Maiden) planted at densities of 2220, 3330, 4440 and 6660 trees ha-1, for a period of 57 months in northern (Tacuarembó) and western (Paysandú) regions of Uruguay. Linear and logarithmic equations of individual volume were fitted by site and species. The survival of E. grandis, E. benthamii and E. dunnii was not related to planting density, and the highest mortality values occurred in Tacuarembó. The effects of competition among trees were more evident at the highest planting density for E. grandis. In all species, the reduction in diameter was more marked than that of height, as planting density increased. Tree volume showed the same trend, and this was higher with higher planting densities. At Tacuarembó, the volume was the highest with E. benthamii at 6660 trees ha-1 (416.4 m3 ha-1), and, at Paysandú, the highest production was obtained with E. grandis (370.7 m3 ha-1) and with the densities of 4440 and 6660 trees ha-1 (305.9 and 315.3 m3 ha-1, respectively). With all species and planting densities, there was an incre... Presentar Todo |
|
Palabras claves : |
ALLOMETRICS MODELS; EUCALYPTUS; PLANTING DENSITY; SHORT ROTATION; SURVIVAL. |
|
Thesagro : |
FORESTACIÓN. |
|
Asunto categoría : |
K10 Producción forestal |
|
Marc : |
LEADER 03580naa a2200277 a 4500
001 1059321
005 2020-02-04
008 2018 bl uuuu u00u1 u #d
024 7 $a10.3390/f9120745$2DOI
100 1 $aRESQUÍN, F.
245 $aAllometry, Growth and Survival of Three Eucalyptus Species (Eucalyptus benthamii Maiden and Cambage, E. dunnii Maiden and E. grandis Hill ex Maiden) in High-Density Plantations in Uruguay.$h[electronic resource]
260 $c2018
500 $aArticle history: Received: 18 October 2018; Accepted: 13 November 2018; Published: 29 November 2018. Author Contributions: F.R., C.R.-C. and L.C.-L. planned and designed the research. F.R. and C.R.-C. conducted fieldwork and performed experiments. R.M.N.-C., A.H. and J.D.-L. contributed to data elaboration and analysis. F.R., R.M.N.-C. and L.C.-L. wrote the manuscript, with contributions by all authors. // Funding: This study was funded by the National Research Institute of Agriculture Research (INIA) and National Agency for Research and Innovation (ANII) through the grant FSE 1 2011 15615 (Evaluación productiva y ambiental de plantaciones forestales para la generación de Bioenergía). Acknowledgments: The authors thank the INIA, ANII and Forestal Oriental company for its collaboration with the field experiments and plantations
520 $aThis study presents a yield model for aboveground biomass production from three species the Eucalyptus in northern and western regions of Uruguay, based on sampling records from intensive crop plantations. High-density eucalyptus plantations represent a forestry alternative for the production of forest biomass. This work assessed the survival and growth of three eucalyptus species (Eucalyptus benthamii Maiden & Cambage, E. dunnii Maiden and E. grandis Hill ex Maiden) planted at densities of 2220, 3330, 4440 and 6660 trees ha-1, for a period of 57 months in northern (Tacuarembó) and western (Paysandú) regions of Uruguay. Linear and logarithmic equations of individual volume were fitted by site and species. The survival of E. grandis, E. benthamii and E. dunnii was not related to planting density, and the highest mortality values occurred in Tacuarembó. The effects of competition among trees were more evident at the highest planting density for E. grandis. In all species, the reduction in diameter was more marked than that of height, as planting density increased. Tree volume showed the same trend, and this was higher with higher planting densities. At Tacuarembó, the volume was the highest with E. benthamii at 6660 trees ha-1 (416.4 m3 ha-1), and, at Paysandú, the highest production was obtained with E. grandis (370.7 m3 ha-1) and with the densities of 4440 and 6660 trees ha-1 (305.9 and 315.3 m3 ha-1, respectively). With all species and planting densities, there was an increase in the accumulated volume during the 57-month study period; however, growth curves indicate that the maximum production per unit time and, therefore, the optimum harvest time occurred at 48 months. In this work, it has been shown that the use of intensive short-rotation plantations of eucalyptus for the production of biomass in Uruguay is suitable in soils prioritized for forestry.
650 $aFORESTACIÓN
653 $aALLOMETRICS MODELS
653 $aEUCALYPTUS
653 $aPLANTING DENSITY
653 $aSHORT ROTATION
653 $aSURVIVAL
700 1 $aNAVARRO-CERRILLO, R.M.
700 1 $aRACHID, C.
700 1 $aHIRIGOYEN, A.
700 1 $aCARRASCO-LETELIER, L.
700 1 $aDUQUE-LAZO, J.
773 $tForests 2018.
Descargar
Esconder MarcPresentar Marc Completo |
|
Registro original : |
INIA Tacuarembó (TBO) |
|
|
Biblioteca
|
Identificación
|
Origen
|
Tipo / Formato
|
Clasificación
|
Cutter
|
Registro
|
Volumen
|
Estado
|
Volver
|
| Expresión de búsqueda válido. Check! |
|
|
