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 | Acceso al texto completo restringido a Biblioteca INIA Las Brujas. Por información adicional contacte bibliolb@inia.org.uy. |
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Registro completo
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Biblioteca (s) : |
INIA Las Brujas. |
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Fecha : |
02/05/2025 |
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Actualizado : |
02/05/2025 |
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Tipo de producción científica : |
Artículos en Revistas Indexadas Internacionales |
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Autor : |
VASCONCELOS DE SOUSA, A. L.; RIET-CORREA, F.; BOTELHO DE CASTRO, M.; MACHADO, M. |
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Afiliación : |
ANA LÍVIA VASCONCELOS DE SOUSA, Programa de Pós-graduação em Ciências Animais, Universidade de Brasília (UnB), Distrito Federal, Brazil; Laboratório de Patologia e Perícia Veterinária, Campus Darcy Ribeiro, Universidade de Brasília (UnB), Distrito Federal, Brazil; FRANKLIN RIET-CORREA AMARAL, Programa de Pós-graduação em Ciência Animal nos Trópicos, Universidade Federal da Bahia (UFBA), Bahia, Salvador, Brazil; MÁRCIO BOTELHO DE CASTRO, Programa de Pós-graduação em Ciências Animais, Universidade de Brasília (UnB), Distrito Federal, Brazil; Laboratório de Patologia e Perícia Veterinária, Campus Darcy Ribeiro, Universidade de Brasília (UnB), Distrito Federal, Brazil; MIZAEL MACHADO DA COSTA, INIA (Instituto Nacional de Investigación Agropecuaria), Uruguay; Programa de Pós-graduação em Ciências Animais, Universidade de Brasília (UnB), Distrito Federal, Brazil; ORCID: https://orcid.org/0000-0002-2029-884X. |
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Título : |
Sorghum poisoning in ruminants and horses: a review. |
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Complemento del título : |
Review. |
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Fecha de publicación : |
2025 |
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Fuente / Imprenta : |
Toxicon, July 2025, Volume 261, 108375. https://doi.org/10.1016/j.toxicon.2025.108375 |
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ISSN : |
0041-0101 |
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DOI : |
10.1016/j.toxicon.2025.108375 |
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Idioma : |
Inglés |
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Notas : |
Article history: Received 8 March 2025, Received in revised form 14 April 2025, Accepted 23 April 2025, Available online 24 April 2025. -- Correspondence: Machado, M.; Programa de Pós-graduação em Ciências Animais, Universidade de Brasília (UnB), Distrito Federal, Brazil; email:mmachado@inia.org.uy -- Handling Editor: Denise Tambourgi. -- Publisher: Elsevier Ltd. |
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Contenido : |
ABSTRACT.- We reviewed the history, epidemiology, clinical signs, pathology, pathogenesis, treatment, control, and prophylaxis of Sorghum poisoning in livestock. Economic losses in the livestock industry associated with sorghum have been reported since the 19th century. Hyperacute/acute poisoning associated with cyanide (HCN) or nitrate/nitrite frequently occurs in ruminants that consume high quantities of growth and regrowth sorghum after drought, followed by rainfall, respectively. Chronic cystitis-ataxia syndrome primarily affects horses after weeks of grazing on sorghum pastures, while congenital arthrogryposis and axonopathy have been observed in pregnant ewes and cows grazing sorghum sprouts. The hyperacute/acute manifestations result from the blockade of the respiratory chain by cyanide. However, the pathogenesis of chronic exposure leading to spinal cord lesions, as well as the potential teratogenic effects of cyanide, including abortions and limb deformities in both livestock and humans, remains unknown. Sodium thiosulphate is recommended for the treatment of acute poisoning. Prophylaxis for sorghum poisoning includes avoiding grazing on plants younger than seven weeks, removing sorghum from the diet of poisoned animals, and being cautious with sorghum stover after rain due to regrowth
risks. © 2025 Published by Elsevier Ltd. |
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Palabras claves : |
Arthrogryposis; Cyanogenic glycosides; Cystitis-ataxia syndrome; Hydrocyanic acid; Nitrate; PLATAFORMA DE INVESTIGACIÓN EN SALUD ANIMAL - INIA. |
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Asunto categoría : |
L73 Enfermedades de los animales |
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Marc : |
LEADER 02552naa a2200265 a 4500
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022 $a0041-0101
024 7 $a10.1016/j.toxicon.2025.108375$2DOI
100 1 $aVASCONCELOS DE SOUSA, A. L.
245 $aSorghum poisoning in ruminants and horses$ba review.$h[electronic resource]
260 $c2025
500 $aArticle history: Received 8 March 2025, Received in revised form 14 April 2025, Accepted 23 April 2025, Available online 24 April 2025. -- Correspondence: Machado, M.; Programa de Pós-graduação em Ciências Animais, Universidade de Brasília (UnB), Distrito Federal, Brazil; email:mmachado@inia.org.uy -- Handling Editor: Denise Tambourgi. -- Publisher: Elsevier Ltd.
520 $aABSTRACT.- We reviewed the history, epidemiology, clinical signs, pathology, pathogenesis, treatment, control, and prophylaxis of Sorghum poisoning in livestock. Economic losses in the livestock industry associated with sorghum have been reported since the 19th century. Hyperacute/acute poisoning associated with cyanide (HCN) or nitrate/nitrite frequently occurs in ruminants that consume high quantities of growth and regrowth sorghum after drought, followed by rainfall, respectively. Chronic cystitis-ataxia syndrome primarily affects horses after weeks of grazing on sorghum pastures, while congenital arthrogryposis and axonopathy have been observed in pregnant ewes and cows grazing sorghum sprouts. The hyperacute/acute manifestations result from the blockade of the respiratory chain by cyanide. However, the pathogenesis of chronic exposure leading to spinal cord lesions, as well as the potential teratogenic effects of cyanide, including abortions and limb deformities in both livestock and humans, remains unknown. Sodium thiosulphate is recommended for the treatment of acute poisoning. Prophylaxis for sorghum poisoning includes avoiding grazing on plants younger than seven weeks, removing sorghum from the diet of poisoned animals, and being cautious with sorghum stover after rain due to regrowth risks. © 2025 Published by Elsevier Ltd.
653 $aArthrogryposis
653 $aCyanogenic glycosides
653 $aCystitis-ataxia syndrome
653 $aHydrocyanic acid
653 $aNitrate
653 $aPLATAFORMA DE INVESTIGACIÓN EN SALUD ANIMAL - INIA
700 1 $aRIET-CORREA, F.
700 1 $aBOTELHO DE CASTRO, M.
700 1 $aMACHADO, M.
773 $tToxicon, July 2025, Volume 261, 108375. https://doi.org/10.1016/j.toxicon.2025.108375
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