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Registro completo
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Biblioteca (s) : |
INIA Las Brujas. |
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Fecha : |
31/07/2017 |
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Actualizado : |
13/12/2022 |
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Tipo de producción científica : |
Artículos en Revistas Indexadas Internacionales |
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Autor : |
MOTTA, R. R.; SILVA, F. F.; LOPES, P. S.; TEMPELMAN, R. J.; SOLLERO, B. P.; AGUILAR, I.; CARDOSO, F. F. |
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Afiliación : |
R. R. MOTTA, Gembloux Agro-Bio Tech Faculty, TERRA Teaching and Research Centre, University of Liège, Gembloux, Belgium; F. F. SILVA, Department of Animal Science, Universidade Federal de Viçosa, Minas Gerais, Brazil; P. S. LOPES, Department of Animal Science, Universidade Federal de Viçosa, Minas Gerais, Brazil; R. J. TEMPELMAN, Department of Animal Science, Michigan State University, MI, USA; B. P. SOLLERO, Embrapa Pecuária Sul, Rio Grande do Sul, Brazil; IGNACIO AGUILAR GARCIA, INIA (Instituto Nacional de Investigación Agropecuaria), Uruguay; F. F. CARDOSO, Embrapa Pecuária Sul, Rio Grande do Sul, Brazil; 6 Programa de Pós-graduação em Zootecnia, Universidade Federal de Pelotas, Rio Grande do Sul, Brazil. |
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Título : |
Analyses of reaction norms reveal new chromosome regions associated with tick resistance in cattle. |
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Fecha de publicación : |
2018 |
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Fuente / Imprenta : |
Animal, 2018, volume 12, Issue 2, pages 205-214. OPEN ACCESS. doi: https://doi.org/10.1017/S1751731117001562 |
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DOI : |
10.1017/S1751731117001562 |
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Idioma : |
Inglés |
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Notas : |
Article history: Received 12 December 2016; Accepted 22 May 2017; Published online: 13 July 2017.
Corresponding author: R.R. Mota, Gembloux Agro-Bio Tech Faculty, TERRA Teaching and Research Centre, University of Liège, B-5030 Gembloux, Belgium,
rrmota@ulg.ac.be -- License Under a Creative Commons. |
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Contenido : |
ABSTRACT.- Despite single nucleotide polymorphism (SNP) availability and frequent cost reduction has allowed genome-wide association studies even in complex traits as tick resistance, the use of this information source in SNP by environment interaction context is unknown for many economically important traits in cattle. We aimed at identifying putative genomic regions explaining differences in tick resistance in Hereford and Braford cattle under SNP by environment point of view as well as to identify candidate genes derived from outliers/significant markers. The environment was defined as contemporary group means of tick counts, since they seemed to be the most appropriate entities to describe the environmental gradient in beef cattle. A total of 4363 animals having tick counts (n=10 673) originated from 197 sires and 3966 dams were used. Genotypes were acquired on 3591 of these cattle. From top 1% SNPs (410) having the greatest effects in each environment, 75 were consistently relevant in all environments, which indicated SNP by environment interaction. The outliers/significant SNPs were mapped on chromosomes 1, 2, 5, 6, 7, 9, 11, 13, 14, 15, 16, 18, 21, 23, 24, 26 and 28, and potential candidate genes were detected across environments. The presence of SNP by environment interaction for tick resistance indicates that genetic expression of resistance depends upon tick burden. Markers with major portion of genetic variance explained across environments appeared to be close to genes with different direct or indirect functions related to immune system, inflammatory process and mechanisms of tissue destruction/repair, such as energy metabolism and cell differentiation. © The Animal Consortium 2017 MenosABSTRACT.- Despite single nucleotide polymorphism (SNP) availability and frequent cost reduction has allowed genome-wide association studies even in complex traits as tick resistance, the use of this information source in SNP by environment interaction context is unknown for many economically important traits in cattle. We aimed at identifying putative genomic regions explaining differences in tick resistance in Hereford and Braford cattle under SNP by environment point of view as well as to identify candidate genes derived from outliers/significant markers. The environment was defined as contemporary group means of tick counts, since they seemed to be the most appropriate entities to describe the environmental gradient in beef cattle. A total of 4363 animals having tick counts (n=10 673) originated from 197 sires and 3966 dams were used. Genotypes were acquired on 3591 of these cattle. From top 1% SNPs (410) having the greatest effects in each environment, 75 were consistently relevant in all environments, which indicated SNP by environment interaction. The outliers/significant SNPs were mapped on chromosomes 1, 2, 5, 6, 7, 9, 11, 13, 14, 15, 16, 18, 21, 23, 24, 26 and 28, and potential candidate genes were detected across environments. The presence of SNP by environment interaction for tick resistance indicates that genetic expression of resistance depends upon tick burden. Markers with major portion of genetic variance explained across environments appeared to be close to... Presentar Todo |
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Palabras claves : |
BEEF CATTLE; CANDIDATE GENES; ENVIRONMENT GRADIENT; GENE FUNCTION; SINGLE-STEP. |
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Asunto categoría : |
-- |
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URL : |
https://ainfo.inia.uy/digital/bitstream/item/16916/1/10.1017-S1751731117001562.pdf
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Marc : |
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024 7 $a10.1017/S1751731117001562$2DOI
100 1 $aMOTTA, R. R.
245 $aAnalyses of reaction norms reveal new chromosome regions associated with tick resistance in cattle.$h[electronic resource]
260 $c2018
500 $aArticle history: Received 12 December 2016; Accepted 22 May 2017; Published online: 13 July 2017. Corresponding author: R.R. Mota, Gembloux Agro-Bio Tech Faculty, TERRA Teaching and Research Centre, University of Liège, B-5030 Gembloux, Belgium, rrmota@ulg.ac.be -- License Under a Creative Commons.
520 $aABSTRACT.- Despite single nucleotide polymorphism (SNP) availability and frequent cost reduction has allowed genome-wide association studies even in complex traits as tick resistance, the use of this information source in SNP by environment interaction context is unknown for many economically important traits in cattle. We aimed at identifying putative genomic regions explaining differences in tick resistance in Hereford and Braford cattle under SNP by environment point of view as well as to identify candidate genes derived from outliers/significant markers. The environment was defined as contemporary group means of tick counts, since they seemed to be the most appropriate entities to describe the environmental gradient in beef cattle. A total of 4363 animals having tick counts (n=10 673) originated from 197 sires and 3966 dams were used. Genotypes were acquired on 3591 of these cattle. From top 1% SNPs (410) having the greatest effects in each environment, 75 were consistently relevant in all environments, which indicated SNP by environment interaction. The outliers/significant SNPs were mapped on chromosomes 1, 2, 5, 6, 7, 9, 11, 13, 14, 15, 16, 18, 21, 23, 24, 26 and 28, and potential candidate genes were detected across environments. The presence of SNP by environment interaction for tick resistance indicates that genetic expression of resistance depends upon tick burden. Markers with major portion of genetic variance explained across environments appeared to be close to genes with different direct or indirect functions related to immune system, inflammatory process and mechanisms of tissue destruction/repair, such as energy metabolism and cell differentiation. © The Animal Consortium 2017
653 $aBEEF CATTLE
653 $aCANDIDATE GENES
653 $aENVIRONMENT GRADIENT
653 $aGENE FUNCTION
653 $aSINGLE-STEP
700 1 $aSILVA, F. F.
700 1 $aLOPES, P. S.
700 1 $aTEMPELMAN, R. J.
700 1 $aSOLLERO, B. P.
700 1 $aAGUILAR, I.
700 1 $aCARDOSO, F. F.
773 $tAnimal, 2018, volume 12, Issue 2, pages 205-214. OPEN ACCESS. doi: https://doi.org/10.1017/S1751731117001562
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Registro original : |
INIA Las Brujas (LB) |
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| Registros recuperados : 8 | |
| 1. |  | LEMA, O.M.; AGUILAR, I.; DIONELLO, N.J.L.; CARDOSO, F.F.; RAVAGNOLO, O.; GIMENO, D. Additive, heterotic and recombination losses for direct and maternal effects in growth for British, Continental and Zebu crosses. In: Proceedings of the World Congress on Genetics Applied to Livestock Production, 11., Aotea Centre Auckland, New Zealand: WCGALP, ICAR, 11-16 feb 2018.| Tipo: Trabajos en Congresos/Conferencias |
| Biblioteca(s): INIA La Estanzuela. |
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| 3. | | LEMA, O.M.; AGUILAR, I.; DIONELLO, N.J.L.; GIMENO, D.; CARDOSO, F.F. Growth performance for crossbreed Hereford, Angus, Salers and Nellore. In: CONGRESO ARGENTINO DE PRODUCCIÓN ANIMAL, 34.; JOINT MEETING AAPA-ASAS, 1., 2011, Mar del Plata. Resúmenes. Mar del Plata: ASAS/AAPA, 2011. Revista Argentina de Producción Animal, v. 31, suppl.1. p. 133, 2011.| Tipo: Abstracts/Resúmenes |
| Biblioteca(s): INIA La Estanzuela. |
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| 4. | | MOTTA, R. R.; SILVA, F. F.; LOPES, P. S.; TEMPELMAN, R. J.; SOLLERO, B. P.; AGUILAR, I.; CARDOSO, F. F. Analyses of reaction norms reveal new chromosome regions associated with tick resistance in cattle. Animal, 2018, volume 12, Issue 2, pages 205-214. OPEN ACCESS. doi: https://doi.org/10.1017/S1751731117001562 Article history: Received 12 December 2016; Accepted 22 May 2017; Published online: 13 July 2017.
Corresponding author: R.R. Mota, Gembloux Agro-Bio Tech Faculty, TERRA Teaching and Research Centre, University of Liège, B-5030 Gembloux,...| Tipo: Artículos en Revistas Indexadas Internacionales | Circulación / Nivel : Internacional - -- |
| Biblioteca(s): INIA Las Brujas. |
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| 5. | | CARDOSO, F. F.; SOLLERO, B. P.; COMIN, H. B.; GOMES, C. G.; ROSO, V. M.; HIGA, R. H.; CAETANO, A. R.; YOKOO, M. J.; AGUILAR, I. Accuracy of genomic prediction for tick resistance in Braford and Hereford cattle. Volume Species Breeding: Beef cattle (Posters), 713. In: Proceedings of the World Congress on Genetics Applied to Livestock Production, 10., Vancouver, BC, Canada, August 17-22, 2014. p.713. Acknowledgments: Research supported by CNPq - National Council for Scientific and Technological Development grant 478992/2012-2, Embrapa - Brazilian Agricultural Research Corporation grants 02.09.07.004 and 01.11.07.002.07, and CAPES -...| Tipo: Trabajos en Congresos/Conferencias |
| Biblioteca(s): INIA Las Brujas. |
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| 6. | | MOTA, R. R.; LOPES, P. S.; TEMPELMAN, R. J.; SILVA, F. F.; AGUILAR, I.; GOMES, C. C. G.; CARDOSO, F. F. Genome-enabled prediction for tick resistance in Hereford and Braford beef cattle via reaction norm models. Journal of Animal Science, May 2016, Volume 94, Issue 5, Pages 1834 - 1843. Article history: Received December 11, 2015. // Accepted March 10, 2016.| Tipo: Artículos en Revistas Indexadas Internacionales | Circulación / Nivel : A - 1 |
| Biblioteca(s): INIA Las Brujas. |
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| 7. | | CARDOSO, F. F.; YOKOO, M. J. I.; GULIAS-GOMES, C. C.; OLIVEIRA, M. M. DE; TEIXEIRA, B. B. M.; ROSO, V. M.; BRITO, F. V.; CAETANO, A. R.; AGUILAR, I. Avaliação genômica de touros Hereford e Braford. Bagé: Embrapa Pecuária Sul, 2012. 32 p. (Embrapa Pecuária Sul. Documentos, 127).| Biblioteca(s): INIA Las Brujas. |
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| 8. | | CARDOSO, F. F.; GOMES, C.C.G.; SOLLERO, B. P.; OLIVEIRA, M. M.; ROSO, V. M.; PICCOLI, M. L.; HIGA, R. H.; YOKOO, M. J.; CAETANO, A. R.; AGUILAR, I. Genomic prediction for tick resistance in Braford and Hereford cattle. Journal of Animal Science, 2015. v. 95, p. 2693-2705. Published June 25, 2015 Article history: Received December 19, 2014 / Accepted April 6, 2015.| Tipo: Artículos en Revistas Indexadas Internacionales | Circulación / Nivel : Internacional - -- |
| Biblioteca(s): INIA Las Brujas. |
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| Registros recuperados : 8 | |
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