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Registros recuperados : 60 | |
4. |  | ABREO, E.; ALTIER, N. (Comp.). Simposio Microorganismos para la agricultura. Resúmenes de presentaciones. Jornada técnica, 27 octubre 2017, INIA Las Brujas (Canelones, UY). Las Brujas, Canelones (UY): INIA, 2017. 57 p. (Serie Actividades de Difusión: 779) A través del sitio web de INIA puede acceder a los documentos, presentaciones y video de la actividad realizada el 20 de octubre de 2017 en INIA Las Brujas.
COMITÉ ORGANIZADOR: Eduardo Abreo, Nora Altier, Elena Beyhaut, Santiago Cayota,...Biblioteca(s): INIA Las Brujas. |
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5. |  | ABREO, E.; ALTIER, N. (Comp.). Taller de Agentes Microbianos de Control Biológico, 4., Resúmenes de presentaciones. Montevideo, 31 Octubre, 2014. Montevideo (UY): INIA, 2014. 26 p. COMITÉ ORGANIZADOR: Eduardo Abreo (INIA Las Brujas), Nora Altier (INIA Las Brujas), Alicia Arias (IIBCE), Natalia Bajsa (IIBCE), Enrique Castiglioni (CURE, UDELAR), Lyliam Loperena (Facultad de Ingeniería, UDELAR), Sandra Lupo (Facultad...Biblioteca(s): INIA Las Brujas. |
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6. |  | SESSA, L.; ABREO, E.; LUPO, S. Diaporthe y Botryosphaeriaceae: endófitos verdaderos y patógenos latentes asociados a frutales en Uruguay. [p.16]. Bloque 1: Detección y caracterización de plagas y enfermedades. In: Sociedad Uruguaya de Fitopatología Jornada Uruguaya de Fitopatología, 4., Jornada Uruguaya de Protección Vegetal, 2., 1° setiembre, 2017, Montevideo, Uruguay. Libro de resúmenes. Montevideo (UY): Sociedad Uruguay de Fitopatología (SUFIT), 2017. p. 31. Financiamiento: Agencia Nacional de Investigación e Innovación (ANII).Biblioteca(s): INIA Las Brujas. |
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9. |  | ABREO, E.; BEYHAUT, E.; RIVAS, F. (Ed.). Simposio Microorganismos para la Agricultura, 2. [Resúmenes y Posters]. Simposio, 2, 27-28 setiembre 2022, INIA Las Brujas (Canelones, UY). Canelones (UY): INIA, 2022. 62 p. (Serie Actividades de Difusión; 801). Los días 27 y 28 de setiembre, se llevó a cabo en INIA Las Brujas el 2° Simposio Microorganismos para la agricultura. Fue un ámbito para el encuentro y comunicación de los avances científicos y técnicos que se han generado en la academia,...Biblioteca(s): INIA Las Brujas. |
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11. |  | SANGUIÑEDO, P.; ABREO, E.; ALBORÉS, S. Síntesis de nanopartículas biogénicas a partir de Trichoderma spp. y su aplicación en el control de fitopatógenos. P14. Módulo 4: Avances en tecnologías de formulación y aplicación. In: Abreo, E.; Beyhaut, E.; Rivas, F. (Eds.). Simposio Microorganismos para la Agricultura, 2. [Resúmenes y Posters]. Canelones (UY): INIA, 2022. p.35. (Serie Actividades de Difusión; 801). Financiamiento: Proyecto INNOVAGRO ANII FSA_1_2018_1_152546,PEDECIBA QUÍMICA, Beca ANII, Beca CAP, Posgrado en Biotecnología-UDELAR.Biblioteca(s): INIA Las Brujas. |
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13. |  | ALTIER, N.; ABREO, E.; BEYHAUT, E.; RIVAS, F.; GARAYCOCHEA, S. Beneficial microbes for agriculture in Uruguay: strategies and successful case studies. (O19-3). [Abstract]. XIX International Plant Protection Congress, IPPC 2019. 10-14 November 2019, Hyderabad, Telangana, India. "Crop Protection to Outsmart Climate Change for Food Security & Environmental Conservation”. Organized by ICRISAT (International Crops Research Institute for the Semi-Arid Tropics). In: INTERNATIONAL PLANT PROTECTION CONGRESS, 19, 2019, Hyderabad, India. Abstract Book... Hyderabad: IPPC, 2019. p. 99.Biblioteca(s): INIA Las Brujas. |
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14. |  | ABREO, E.; VAZ, P.; NÚÑEZ, L.; STEWART, S.; ALTIER, N. Caracterización molecular y virulencia de aislamientos de Pythium spp. obtenidos en suelos de Uruguay. In: JORNADA NACIONAL DE FITOPATOLOGÍA, 3; JORNADA NACIONAL DE PROTECCIÓN VEGETAL, 1., 3 SETIEMBRE 2015, MONTEVIDEO, URUGUAY. Libro de Resúmenes. Montevideo (Uruguay) : SUFIT, 2015. p. 29Biblioteca(s): INIA Las Brujas. |
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17. |  | SESSA, L.; ABREO, E.; BETTUCCI, L.; LUPO, S. Botryosphaeriaceae: identificación, patogenicidad y detección temprana de especies patógenas de duraznero, peral y manzano en Uruguay. In: JORNADA NACIONAL DE FITOPATOLOGÍA, 3; JORNADA NACIONAL DE PROTECCIÓN VEGETAL, 1., 3 SETIEMBRE 2015, MONTEVIDEO, URUGUAY. Libro de Resúmenes. Montevideo (Uruguay) : SUFIT, 2015. p. 48 Financiamiento: Agencia Nacional de Investigación e Innovación (ANII).Biblioteca(s): INIA Las Brujas. |
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20. |  | SESSA, L.; PEDRINI, N.; ALTIER, N.; ABREO, E. Conociendo al enemigo: Hidrocarburos epicuticulares de insectos plaga y su utilización para el biocontrol. O11. Módulo 3: Nuevas estrategias para potenciar el control biológico. In: Abreo, E.; Beyhaut, E.; Rivas, F. (Eds.). Simposio Microorganismos para la Agricultura, 2. [Resúmenes y Posters]. Canelones (UY): INIA, 2022. p.22. (Serie Actividades de Difusión; 801). Financiamiento: Beca ANII, INIA, Beca CAP.Biblioteca(s): INIA Las Brujas. |
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Registros recuperados : 60 | |
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 | Acceso al texto completo restringido a Biblioteca INIA Las Brujas. Por información adicional contacte bibliolb@inia.org.uy. |
Registro completo
|
Biblioteca (s) : |
INIA Las Brujas. |
Fecha actual : |
26/02/2024 |
Actualizado : |
26/02/2024 |
Tipo de producción científica : |
Artículos en Revistas Indexadas Internacionales |
Circulación / Nivel : |
Internacional - -- |
Autor : |
COSTA, M.; MANSILLA, F.; MANUEL SALA, J.; SARAVIA, A.; UBIOS, D.; LORES, P.; CAPOZZO, A.V.; FREIRE, T. |
Afiliación : |
MONIQUE COSTA, Laboratorio de Inmunomodulación y Vacunas, Departamento de Inmunobiología, Facultad de Medicina, Universidad de La República, Montevideo, Uruguay; FLORENCIA MANSILLA, Instituto de Virología e Innovaciones Tecnológicas, Centro de Investigaciones en Ciencias Veterinarias y Agronómicas (CICVyA), INTA, Buenos Aires, Hurlingham, Argentina; JUAN MANUEL SALA, Estación Experimental Agropecuaria- Instituto Nacional de Tecnología Agropecuaria (INTA), Juan Pujol al Este s/n (3470), Corrientes, Mercedes, Argentina; ANDERSON SARAVIA DE MELO, INIA (Instituto Nacional de Investigación Agropecuaria), Uruguay; DIEGO UBIOS, INIA (Instituto Nacional de Investigación Agropecuaria), Uruguay; PABLO LORES, Laboratorio de Inmunomodulación y Vacunas, Departamento de Inmunobiología, Facultad de Medicina, Universidad de La República, Montevideo, Uruguay; ALEJANDRA VICTORIA CAPOZZO, Instituto de Virología e Innovaciones Tecnológicas, Centro de Investigaciones en Ciencias Veterinarias y Agronómicas (CICVyA), INTA, Buenos Aires, Hurlingham, Argentina; Consejo Nacional de Investigaciones Científicas y Técnicas (CONICET), Argentina; TERESA FREIRE, Laboratorio de Inmunomodulación y Vacunas, Departamento de Inmunobiología, Facultad de Medicina, Universidad de La República, Montevideo. |
Título : |
Fasciola hepatica infection modifies lgG1 specific immune response to foot-and-mouth disease virus induced by vaccination. |
Fecha de publicación : |
2024 |
Fuente / Imprenta : |
Vaccine. 2024, Volume 42, Issue 3, Pages 541-547. https://doi.org/10.1016/j.vaccine.2023.12.067 |
ISSN : |
0264-410X |
DOI : |
10.1016/j.vaccine.2023.12.067 |
Idioma : |
Inglés |
Notas : |
Article history: Received 19 August 2023; Received in revised form 15 December 2023; Accepted 20 December 2023; Available online 6 January 2024. -- Correspondence: Freire, T.; UdelaR, Facultad de Medicina, Departamento de Inmunobiología, Gral. Flores 2125, Montevideo, Uruguay; email:tfreire@fmed.edu.uy -- Funding: Financial supports were provided by Programa de Desarrollo de Ciencias Básicas ( PEDECIBA ), Comisión Sectorial de Investigación Científica and Agencia Nacional de Investigación e Innovación (SNI-ANII and FCE_1_2019_1_156295) to Teresa Freire. Funding by GFRA Research to Florencia Mansilla was also provided. M. Costa was funded by ANII and CAP. A. V. Capozzo is a researcher of CONICET , Argentina. -- Supplementary data to this article can be found online at https://doi.org/10.1016/j.vaccine.2023.12.067 |
Contenido : |
ABSTRACT.- Fasciola hepatica, a worldwide distributed helminth, has a robust immunoregulatory effect in the host, increasing the susceptibility to secondary infections. Foot and mouth disease (FMD) is a highly contagious acute vesicular viral disease effectively controlled by vaccination in endemic regions. Despite the evidence of immunoregulatory effects, the impact of fasciolosis on the immune response induced by FMD vaccination in cattle has never been assessed. Our objective was to evaluate whether the infection by F. hepatica in cattle influences the long-term immunity elicited by the currently used commercial FMD-inactivated vaccines. Aberdeen Angus steers negative for F. hepatica were vaccinated twice against FMD virus (FMDV) during the first 6 months of age using a commercial oil vaccine formulated with A24/Cruzeiro and O1/Campos strains. When maternal antibodies against F. hepatica were weaned (18--20 months of age) animals were divided into groups of 12 and infected or mock-infected with 500 metacercariae/animal. Individual serum samples were collected at 0-, 28-, 59-, 87- and 157-days post-infection (dpi). Indirect ELISAs were used to detect A24/Cruzeiro specific bovine IgG and IgG subtypes. The total IgG antibody levels and avidity against FMDV did not show significant differences between all the groups. The commercial vaccine induced higher IgG2 than IgG1 titers in vaccinated animals. Anti-FMDV IgG1 levels significantly decreased in the infected group at 28 dpi. In addition, the avidity of IgG1 FMDV-specific antibodies at day 28 in the infected group was reduced compared to the control. These results show that F. hepatica infection modified anamnestic responses against FMDV, reducing serum IgG1 titers and avidity. To our knowledge, this is the first report of immune-regulation of F. hepatica altering the immune response of FMD vaccines, one of the most globally used animal vaccines. © 2024 Elsevier Ltd MenosABSTRACT.- Fasciola hepatica, a worldwide distributed helminth, has a robust immunoregulatory effect in the host, increasing the susceptibility to secondary infections. Foot and mouth disease (FMD) is a highly contagious acute vesicular viral disease effectively controlled by vaccination in endemic regions. Despite the evidence of immunoregulatory effects, the impact of fasciolosis on the immune response induced by FMD vaccination in cattle has never been assessed. Our objective was to evaluate whether the infection by F. hepatica in cattle influences the long-term immunity elicited by the currently used commercial FMD-inactivated vaccines. Aberdeen Angus steers negative for F. hepatica were vaccinated twice against FMD virus (FMDV) during the first 6 months of age using a commercial oil vaccine formulated with A24/Cruzeiro and O1/Campos strains. When maternal antibodies against F. hepatica were weaned (18--20 months of age) animals were divided into groups of 12 and infected or mock-infected with 500 metacercariae/animal. Individual serum samples were collected at 0-, 28-, 59-, 87- and 157-days post-infection (dpi). Indirect ELISAs were used to detect A24/Cruzeiro specific bovine IgG and IgG subtypes. The total IgG antibody levels and avidity against FMDV did not show significant differences between all the groups. The commercial vaccine induced higher IgG2 than IgG1 titers in vaccinated animals. Anti-FMDV IgG1 levels significantly decreased in the infected group at 28 dpi.... Presentar Todo |
Palabras claves : |
Fasciolosis; FMD vaccine; IgG avidity; Immune modulation; PLATAFORMA DE INVESTIGACIÓN EN SALUD ANIMAL - INIA; Vaccine efficacy. |
Asunto categoría : |
L01 Ganadería |
Marc : |
LEADER 03751naa a2200313 a 4500 001 1064474 005 2024-02-26 008 2024 bl uuuu u00u1 u #d 022 $a0264-410X 024 7 $a10.1016/j.vaccine.2023.12.067$2DOI 100 1 $aCOSTA, M. 245 $aFasciola hepatica infection modifies lgG1 specific immune response to foot-and-mouth disease virus induced by vaccination.$h[electronic resource] 260 $c2024 500 $aArticle history: Received 19 August 2023; Received in revised form 15 December 2023; Accepted 20 December 2023; Available online 6 January 2024. -- Correspondence: Freire, T.; UdelaR, Facultad de Medicina, Departamento de Inmunobiología, Gral. Flores 2125, Montevideo, Uruguay; email:tfreire@fmed.edu.uy -- Funding: Financial supports were provided by Programa de Desarrollo de Ciencias Básicas ( PEDECIBA ), Comisión Sectorial de Investigación Científica and Agencia Nacional de Investigación e Innovación (SNI-ANII and FCE_1_2019_1_156295) to Teresa Freire. Funding by GFRA Research to Florencia Mansilla was also provided. M. Costa was funded by ANII and CAP. A. V. Capozzo is a researcher of CONICET , Argentina. -- Supplementary data to this article can be found online at https://doi.org/10.1016/j.vaccine.2023.12.067 520 $aABSTRACT.- Fasciola hepatica, a worldwide distributed helminth, has a robust immunoregulatory effect in the host, increasing the susceptibility to secondary infections. Foot and mouth disease (FMD) is a highly contagious acute vesicular viral disease effectively controlled by vaccination in endemic regions. Despite the evidence of immunoregulatory effects, the impact of fasciolosis on the immune response induced by FMD vaccination in cattle has never been assessed. Our objective was to evaluate whether the infection by F. hepatica in cattle influences the long-term immunity elicited by the currently used commercial FMD-inactivated vaccines. Aberdeen Angus steers negative for F. hepatica were vaccinated twice against FMD virus (FMDV) during the first 6 months of age using a commercial oil vaccine formulated with A24/Cruzeiro and O1/Campos strains. When maternal antibodies against F. hepatica were weaned (18--20 months of age) animals were divided into groups of 12 and infected or mock-infected with 500 metacercariae/animal. Individual serum samples were collected at 0-, 28-, 59-, 87- and 157-days post-infection (dpi). Indirect ELISAs were used to detect A24/Cruzeiro specific bovine IgG and IgG subtypes. The total IgG antibody levels and avidity against FMDV did not show significant differences between all the groups. The commercial vaccine induced higher IgG2 than IgG1 titers in vaccinated animals. Anti-FMDV IgG1 levels significantly decreased in the infected group at 28 dpi. In addition, the avidity of IgG1 FMDV-specific antibodies at day 28 in the infected group was reduced compared to the control. These results show that F. hepatica infection modified anamnestic responses against FMDV, reducing serum IgG1 titers and avidity. To our knowledge, this is the first report of immune-regulation of F. hepatica altering the immune response of FMD vaccines, one of the most globally used animal vaccines. © 2024 Elsevier Ltd 653 $aFasciolosis 653 $aFMD vaccine 653 $aIgG avidity 653 $aImmune modulation 653 $aPLATAFORMA DE INVESTIGACIÓN EN SALUD ANIMAL - INIA 653 $aVaccine efficacy 700 1 $aMANSILLA, F. 700 1 $aMANUEL SALA, J. 700 1 $aSARAVIA, A. 700 1 $aUBIOS, D. 700 1 $aLORES, P. 700 1 $aCAPOZZO, A.V. 700 1 $aFREIRE, T. 773 $tVaccine. 2024, Volume 42, Issue 3, Pages 541-547. https://doi.org/10.1016/j.vaccine.2023.12.067
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