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 | Acceso al texto completo restringido a Biblioteca INIA Las Brujas. Por información adicional contacte bibliolb@inia.org.uy. |
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Registro completo
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Biblioteca (s) : |
INIA Las Brujas. |
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Fecha : |
24/06/2019 |
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Actualizado : |
16/03/2021 |
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Tipo de producción científica : |
Artículos en Revistas Indexadas Internacionales |
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Autor : |
CASAL, A.; GARCÍA-ROCHE, M.; NAVAJAS, E.; CASSINA, A.; CARRIQUIRY, M |
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Afiliación : |
A. CASAL, Departamento de Produccion Animal y Pasturas, Facultad de Agronomia, Universidad de la Republica, Paysandú, Uruguay.; M. GARCÍA-ROCHE, Departamento de Produccion Animal y Pasturas, Facultad de Agronomia, Universidad de la Republica, Montevideo, Uruguay; Center for Free Radical and Biomedical Research (CEINBIO); ELLY ANA NAVAJAS VALENTINI, INIA (Instituto Nacional de Investigación Agropecuaria), Uruguay; A. CASSINA, Center for Free Radical and Biomedical Research (CEINBIO) and Departamento de Bioquímica, Facultad de Medicina, Universidad de la Republica, Montevideo, Uruguay; M. CARRIQUIRY, Departamento de Produccion Animal y Pasturas, Facultad de Agronomia, Universidad de la Republica, Montevideo, Uruguay. |
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Título : |
Differential hepatic oxidative status in steers with divergent residual feed intake phenotype. |
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Fecha de publicación : |
2020 |
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Fuente / Imprenta : |
Animal, 1 January 2020, Volume 14, Issue 1, Pages 78-85. Doi: https://doi.org/10.1017/S1751731119001332 |
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DOI : |
10.1017/S1751731119001332 |
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Idioma : |
Inglés |
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Notas : |
Article history: Received 12 December 2018 // Accepted 6 May 2019 // Published online: 20 June 2019.
Supplementary materials.
Corresponding author: Casal, A.; Departamento de Produccion Animal y Pasturas, Facultad de Agronomia, Universidad de la Republica, Ruta 3 km 363, Paysandu, Uruguay; email:alcas@adinet.com.uy |
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Contenido : |
ABSTRACT.
Oxidative stress occurs when oxidant production exceeds the antioxidant capacity to detoxify the reactive intermediates or to repair the resulting damage. Feed efficiency has been associated with mitochondrial function due to its impact on cell energy metabolism. However, mitochondria are also recognized as a major source of oxidants. The aim of this study was to determine lipid and protein oxidative stress markers, and gene and protein expression as well as activity of antioxidant enzymes in the liver of steers of divergent residual feed intake (RFI) phenotypes. Hereford steers (n = 111) were evaluated in post-weaning 70 days standard test for RFI. Eighteen steers exhibiting the greatest (n = 9; high-RFI) and the lowest (n = 9; low-RFI) RFI values were selected for this study. After the test, steers were managed together under grazing conditions until slaughter when they reached the slaughter body weight. At slaughter, hepatic samples were obtained, were snap-frozen in liquid nitrogen and stored at −80°C until analyses. Hepatic thiobarbituric acid reactive species and protein carbonyls were greater (P = 0.05) and hepatic 4-hydroxynonenal protein adducts tended (P = 0.10) to be greater for high- than low-RFI steers. Hepatic gene expression glutathione peroxidase 4, glutamate?cysteine ligase catalytic subunit and peroxiredoxin 5 mRNA was greater (P ≤ 0.05) and glutathione peroxidase 3 mRNA tended (P = 0.10) to be greater in low- than high-RFI steers. Hepatic protein expression and enzyme activity of manganese superoxide dismutase and glutathione peroxidase enzyme activity tended (P ≤ 0.10) to be greater for low- than high-RFI steers. High-efficiency steers (low-RFI) probably had better hepatic oxidative status which was strongly associated with greater antioxidant ability near to the oxidant production site and, therefore, reduced oxidative stress of the liver. Decreased hepatic oxidative stress would reduce maintenance requirements due to a lower protein and lipid turnover and better efficiency in the use of energy.
© The Animal Consortium 2019 MenosABSTRACT.
Oxidative stress occurs when oxidant production exceeds the antioxidant capacity to detoxify the reactive intermediates or to repair the resulting damage. Feed efficiency has been associated with mitochondrial function due to its impact on cell energy metabolism. However, mitochondria are also recognized as a major source of oxidants. The aim of this study was to determine lipid and protein oxidative stress markers, and gene and protein expression as well as activity of antioxidant enzymes in the liver of steers of divergent residual feed intake (RFI) phenotypes. Hereford steers (n = 111) were evaluated in post-weaning 70 days standard test for RFI. Eighteen steers exhibiting the greatest (n = 9; high-RFI) and the lowest (n = 9; low-RFI) RFI values were selected for this study. After the test, steers were managed together under grazing conditions until slaughter when they reached the slaughter body weight. At slaughter, hepatic samples were obtained, were snap-frozen in liquid nitrogen and stored at −80°C until analyses. Hepatic thiobarbituric acid reactive species and protein carbonyls were greater (P = 0.05) and hepatic 4-hydroxynonenal protein adducts tended (P = 0.10) to be greater for high- than low-RFI steers. Hepatic gene expression glutathione peroxidase 4, glutamate?cysteine ligase catalytic subunit and peroxiredoxin 5 mRNA was greater (P ≤ 0.05) and glutathione peroxidase 3 mRNA tended (P = 0.10) to be greater in low- than high-RFI steers. Hep... Presentar Todo |
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Palabras claves : |
ANTIOXIDANTS; ENERGY METABOLISM; FEED EFFICIENCY; FEEDING; LIVER; OXIDATIVE STRESS. |
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Thesagro : |
ALIMENTACION ANIMAL. |
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Asunto categoría : |
L02 Alimentación animal |
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Marc : |
LEADER 03260naa a2200277 a 4500
001 1059875
005 2021-03-16
008 2020 bl uuuu u00u1 u #d
024 7 $a10.1017/S1751731119001332$2DOI
100 1 $aCASAL, A.
245 $aDifferential hepatic oxidative status in steers with divergent residual feed intake phenotype.$h[electronic resource]
260 $c2020
500 $aArticle history: Received 12 December 2018 // Accepted 6 May 2019 // Published online: 20 June 2019. Supplementary materials. Corresponding author: Casal, A.; Departamento de Produccion Animal y Pasturas, Facultad de Agronomia, Universidad de la Republica, Ruta 3 km 363, Paysandu, Uruguay; email:alcas@adinet.com.uy
520 $aABSTRACT. Oxidative stress occurs when oxidant production exceeds the antioxidant capacity to detoxify the reactive intermediates or to repair the resulting damage. Feed efficiency has been associated with mitochondrial function due to its impact on cell energy metabolism. However, mitochondria are also recognized as a major source of oxidants. The aim of this study was to determine lipid and protein oxidative stress markers, and gene and protein expression as well as activity of antioxidant enzymes in the liver of steers of divergent residual feed intake (RFI) phenotypes. Hereford steers (n = 111) were evaluated in post-weaning 70 days standard test for RFI. Eighteen steers exhibiting the greatest (n = 9; high-RFI) and the lowest (n = 9; low-RFI) RFI values were selected for this study. After the test, steers were managed together under grazing conditions until slaughter when they reached the slaughter body weight. At slaughter, hepatic samples were obtained, were snap-frozen in liquid nitrogen and stored at −80°C until analyses. Hepatic thiobarbituric acid reactive species and protein carbonyls were greater (P = 0.05) and hepatic 4-hydroxynonenal protein adducts tended (P = 0.10) to be greater for high- than low-RFI steers. Hepatic gene expression glutathione peroxidase 4, glutamate?cysteine ligase catalytic subunit and peroxiredoxin 5 mRNA was greater (P ≤ 0.05) and glutathione peroxidase 3 mRNA tended (P = 0.10) to be greater in low- than high-RFI steers. Hepatic protein expression and enzyme activity of manganese superoxide dismutase and glutathione peroxidase enzyme activity tended (P ≤ 0.10) to be greater for low- than high-RFI steers. High-efficiency steers (low-RFI) probably had better hepatic oxidative status which was strongly associated with greater antioxidant ability near to the oxidant production site and, therefore, reduced oxidative stress of the liver. Decreased hepatic oxidative stress would reduce maintenance requirements due to a lower protein and lipid turnover and better efficiency in the use of energy. © The Animal Consortium 2019
650 $aALIMENTACION ANIMAL
653 $aANTIOXIDANTS
653 $aENERGY METABOLISM
653 $aFEED EFFICIENCY
653 $aFEEDING
653 $aLIVER
653 $aOXIDATIVE STRESS
700 1 $aGARCÍA-ROCHE, M.
700 1 $aNAVAJAS, E.
700 1 $aCASSINA, A.
700 1 $aCARRIQUIRY, M
773 $tAnimal, 1 January 2020, Volume 14, Issue 1, Pages 78-85. Doi: https://doi.org/10.1017/S1751731119001332
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| 2. |  | BRIANO, C.; MEIKLE, A.; VELAZCO, J.I.; QUINTANS, G. Metabolic and hormonal profiles and productive performance in primiparous and multiparous cows grazing different forage allowance in late gestation. Theriogenology, 2024, Volume 227, Pages 68-76. https://doi.org/10.1016/j.theriogenology.2024.07.007 Article history: Received 8 December 2023; Received in revised form 5 July 2024; Accepted 8 July 2024; Available online 9 July 2024. -- Corresponding author: Briano, C.; Lautaro Guerra 1626, Treinta y Tres, Uruguay;...| Tipo: Artículos en Revistas Indexadas Internacionales | Circulación / Nivel : Internacional - -- |
| Biblioteca(s): INIA Las Brujas. |
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| 3. | | BRIANO, C.; SCARSI, A.; VELAZCO, J.I.; BAKKER, M.; BANCHERO, G.; MEIKLE, A.; QUINTANS, G. Alta y baja asignación de forraje antes del parto: efectos sobre variables productivas y reproductivas. Resultados preliminares In: QUINTANS, G.; SCARSI, A. (Eds.). Seminario de actualización técnica: cría vacuna Montevideo (UY): INIA, 2013. p. 175-185 (INIA Serie Técnica; 208)| Tipo: Capítulo en Libro Técnico-Científico |
| Biblioteca(s): INIA La Estanzuela; INIA Las Brujas; INIA Tacuarembó; INIA Treinta y Tres. |
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| 4. | | BRIANO, C.; SCARSI, M.; VELAZCO, J.; BANCHERO, G.; MEIKLE, A.; QUINTANS, G. Alta y baja asignación de forraje antes del parto: I. Efectos sobre variables productivas, metabólicas y hormonales en vacas de carne. En: Congreso Latinoamericano de Producción Animal (ALPA). (23º, 2013, La Habana, Cuba). Actas Congreso.| Tipo: Trabajos en Congresos/Conferencias |
| Biblioteca(s): INIA La Estanzuela; INIA Treinta y Tres. |
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| 6. | | BRANDA, A.; FEDERICI, M.; BRIANO, C.; ROMERO, A.; LLAMBÍ, S.; DUTRA, F.; DALLA RIZZA, M. Avances en la identificación de portadores de la deficiencia en la adhesión leucocitaria bovina en raza Holando. In: JORNADA TÉCNICA, VIII JORNADA DE AGROBIOTECNOLOGÍA. INIA LAS BRUJAS, 30 DE OCTUBRE DE 2014. UNIDAD DE BIOTECNOLOGÍA. Montevideo (Uruguay): INIA, 2014. 7-9 (Actividades de Difusión; 741)| Biblioteca(s): INIA Las Brujas. |
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| 8. | | FEDERICI, M.; BRANDA, A.; BRIANO, C.; LLAMBI, S.; DALLA RIZZA, M.; DUTRA, F. Identificación de portadores de la deficiencia en la uridina monofosfato sintasa (DUMPS) en terneras de recría de la cuenca lechera en Uruguay. [Resumen]. Congreso de la Asociación Latinoamericana de Producción Animal, 24.; Congreso de la Sociedad Chilena de Producción Animal, 40., Puerto Varas, Chile, 9 al 13 noviembre 2015. ln: Reunión ALPA (24., Puerto Varas, Chile). Resúmenes. Puerto Varas (Chile): ALPA, 2015. p. 986| Tipo: Abstracts/Resúmenes |
| Biblioteca(s): INIA Las Brujas. |
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| 9. | | BRANDA, A.; FEDERICI, M.; DUTRA, F.; ROMERO, A.; BRIANO, C.; DALLA RIZZA, M.; LLAMBÍ, S. Identificación de terneras Holando portadoras de BLAD y Citrulinemia en la región Este de Uruguay por PCR-RFLP y secuenciación. (Identification of Holstein heifer?s carriers BLAD and Citrullinemia in the eastern region of Uruguay by PCR-RFLP and sequencing). Veterinaria (Montevideo), 2016, v. 52, no. 202, p. 23-27. Recibido :11/5/2015. Aceptado: 28/8/2015| Tipo: Artículos en Revistas Indexadas Nacionales | Circulación / Nivel : Nacional - -- |
| Biblioteca(s): INIA Las Brujas. |
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| 10. | | BRANDA, A.; ROMERO, A.; FEDERICI, M.; BRIANO, C.; DALLA RIZZA, M.; DUTRA, F. Identificación de vacas Polled Hereford portadoras de Msud C248>T mediante PCR-HR, y confirmación por secuenciación. GGM 25 - COMUNICACIONES LIBRES - GGM. GENÓMICA Y GENÉTICA MOLECULAR In: JOURNAL OF BASIC & APPLIED GENETICS, 2016, Vol.27, Iss. 1 (Supp.). XVI LATIN AMERICAN CONGRESS OF GENETICS, IV CONGRESS OF THE URUGUAYAN SOCIETY OF GENETICS, XLIX ANNUAL MEETING OF THE GENETICS SOCIETY OF CHILE, XLV ARGENTINE CONGRESS OF GENETICS, 9-12 October 2016. PROCEEDINGS. Montevideo (Uruguay): SAG, 2016. p. 267| Tipo: Trabajos en Congresos/Conferencias |
| Biblioteca(s): INIA Las Brujas. |
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| 11. | | BRANDA-SICA, A.; FEDERICI, M.; DUTRA, F.; BRIANO, C.; ROMERO, A.; DALLA RIZZA, M.; LLAMBÍ, S. Genotipado de SNPs relacionados con enfermedades hereditarias en terneras Holando utilizando el panel GGP-BovineLDv3. [Genotyping of SNPs related to hereditary diseases in Holstein heifers using the GGP-BovineLDv3 panel.] Sección: Artículos originales. Veterinaria (Montevideo), 2018, v. 54, no. 210, p. 5-10. -- OPEN ACCESS. Artilce history: Recibido 20 Diciembre 2017; Aceptado 20 Agosto 2018; Publicado 1 Noviembre 2018. -- Correspondencia: A. Branda Sica: abranda@inia.org.uy -- Correspondencia: MT. Federici: mfederici@inia.org.uy -- Publicación de la...| Tipo: Artículos en Revistas Indexadas Nacionales | Circulación / Nivel : Nacional - -- |
| Biblioteca(s): INIA Las Brujas. |
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| 13. | | BRIANO, C.; REGIDOR-CERRILLO, J.; EASTON, C.; PIERUCCIONI, F.; ROMERO, A.; PERAZA, P.; MEDEROS, A.; DUTRA, F. Diagnóstico molecular de Neospora caninum en fetos abortados espontáneamente en bovinos de Uruguay. [Molecular diagnosis of Neospora caninum in aborted bovine fetus from Uruguay.]. Sección: Artículos originales. Veterinaria (Montevideo), 2021, v.57(216), e20215721603. doi: https://doi.org/10.29155/VET.57.216.3 Article history: Recibido 16 jul 2020; Aceptado 01 jul 2021; Publicado 29 set 2021. -- Autor para correspondencia: Carolina Briano, e-mail: cbriano@mgap.gub.uy -- Publicación de la Sociedad de Medicina Veterinaria del Uruguay (SMVU).| Tipo: Artículos en Revistas Indexadas Nacionales | Circulación / Nivel : Nacional - -- |
| Biblioteca(s): INIA Las Brujas. |
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| 14. | | FEDERICI, M.; BRANDA, A.; ARTIGAS, R.; BRIANO, C.; ROGBERG, A.; GIOVAMBATTISTA, G.; NICOLINI, P.; DUTRA, F.; LLAMBÍ, S. Plataformas moleculares utilizadas para diagnóstico de enfermedades genéticas en bovinos Holando Uruguayo. [resumen] In: INIA (Instituto Nacional de Investigación Agropecuaria); INIA Las Brujas; Biotecnología. Jornada de Agrobiotecnología, XI. Encuentro Nacional de REDBIO, III. Jornada técnica. Las Brujas, Canelones (UY): INIA, 2018. p.3. (Serie Actividades de Difusión; 786)| Biblioteca(s): INIA Las Brujas. |
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| 15. | | BRANDA, A.; FEDERICI, M.; BRIANO, C.; DUTRA, F.; ARTIGAS, R.; NICOLINI, P.; CAFFARENA, D.; GIANNITTI, F.; DALLA RIZZA, M.; LLAMBÍ, S. Métodos de diagnóstico genético-molecular para identificar enfermedades monogénicas en bovinos Holando. Biotecnología. Revista INIA Uruguay, Junio 2022, no.69, p.47-50. (Revista INIA; 69).| Tipo: Artículos en Revistas Agropecuarias |
| Biblioteca(s): INIA Las Brujas. |
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| 16. | | BRANDA, A.; FEDERICI, M.; GIANNITTI, F.; CAFFARENA, D.; SCHILD, C.; CASAUX, L.; BRIANO, C.; DALLA RIZZA, M.; LLAMBÍ, S.; FRAGA, M.; RIET-CORREA, F.; DUTRA, F. Monitoreo de terneros holando portadores de blad mediante curvas de disociación de alta resolución y secuenciación. In: INIA (Instituto Nacional de Investigación Agropecuaria); INIA Las Brujas; Biotecnología. Jornada de Agrobiotecnología, X. Encuentro Nacional de REDBIO, II. Jornada técnica. Las Brujas, Canelones (UY): INIA, 2017. p. 3-5. (Serie Actividades de Difusión; 780)| Biblioteca(s): INIA Las Brujas. |
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| 17. | | BRIANO, C.; ROMERO, A.; BRANDA, A.; FEDERICI, M.; DALLA RIZZA, M.; LLAMBÍ, S.; GIANNITTI, F.; CAFFARENA, D.; SCHILD, C.; CASAUX, M.L.; DUTRA, F. Principales mutaciones letales y semiletales en terneros Holando de Uruguay. [resumen] In: INIA (Instituto Nacional de Investigación Agropecuaria); INIA Las Brujas; Biotecnología. Jornada de Agrobiotecnología, XI. Encuentro Nacional de REDBIO, III. Jornada técnica. Las Brujas, Canelones (UY): INIA, 2018. p.6-7 (Serie Actividades de Difusión; 786)| Biblioteca(s): INIA Las Brujas. |
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| 18. | | ZARANTONELLI, L.; SUANES, A.; MENY, P.; BURONI, F.; SALVARREY,X.; BRIANO , C.; ASHFIELD, N.; SILVEIRA, C.S.; DUTRA, F.; EASTON, C.; FRAGA, M.; GIANNITTI, F.; HAMOND, C.; MACÍAS-RIOSECO, M.; MENÉNDEZ, C.; MORTOLA, A.; PICARDEAU, M. Isolation of pathogenic Leptospira strains from naturally infected cattle in Uruguay reveals high serovar diversity, and uncovers a relevant risk for human leptospirosis. PLoS Neglected Tropical Diseases, September 2018, vol. 12, Issue 9, Article number e0006694. OPEN ACCESS. Article History: Received: February 8, 2018; Accepted: July 16, 2018; Published: September 13, 2018.| Tipo: Artículos en Revistas Indexadas Internacionales | Circulación / Nivel : Internacional - -- |
| Biblioteca(s): INIA La Estanzuela. |
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| Registros recuperados : 18 | |
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