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 | Acceso al texto completo restringido a Biblioteca INIA Las Brujas. Por información adicional contacte bibliolb@inia.org.uy. |
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Registro completo
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Biblioteca (s) : |
INIA Las Brujas. |
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Fecha : |
20/11/2015 |
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Actualizado : |
24/06/2021 |
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Tipo de producción científica : |
Artículos en Revistas Indexadas Internacionales |
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Autor : |
MACEDO, J.S.; ROCHA, B.P.; COLODEL, E.M.; FREITAS, S.H.; DORIA, R.G.S.; RIET-CORREA, F.; EVENCIO-NETO, J.; MENDONCA, F.S. |
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Afiliación : |
JOSENALDO S. MACEDO; BRENA P. ROCHA; EDSON M. COLODEL; SILVIO H. FREITAS; RENATA G.S. DORIA; FRANKLIN RIET-CORREA, INIA (Instituto Nacional de Investigación Agropecuaria), Uruguay; JOAQUIM EVENCIO-NETO; FABIO S. MENDONCA. |
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Título : |
Congenital malformations caused by Stryphnodendron fissuratum (Leg. Mimosoideae) in guinea pigs (Cavia porcellus). |
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Fecha de publicación : |
2015 |
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Fuente / Imprenta : |
Toxicon, 2015, v. 106, p. 68-71. |
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ISSN : |
0041-0101 |
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DOI : |
10.1016/j.toxicon.2015.09.003 |
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Idioma : |
Inglés |
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Contenido : |
ABSTRACT.
The aim of this study was to evaluate the toxicity of Stryphnodendron fissuratum pods in guinea pigs (Cavia porcellus) and test the hypothesis that this plant has teratogenic effects. Thus, sixteen guinea pigs were randomly divided into four groups of four animals each. Groups 10, 20 and 40 consisted of guinea pigs that received commercial food that contained crushed pods of S. fissuratum at concentrations of 10, 20 and 40 g/kg, respectively, during the period of organogenesis. Control group consisted of guinea pigs under the same management conditions that did not receive crushed pods of S. fissuratum in their food. In all experimental groups, the main clinical signs of poisoning consisted of anorexia, prostration, absence of vocalizations, alopecia, diarrhea, and abortions within the adult guinea pigs. Those that did not abort gave birth to weak, malnourished pups, some of which had fetal malformations. The main teratogenic changes consisted of eventration, arthrogryposis, amelia of the forelimbs, anophthalmia, microphthalmia, anotia and agnathia. The reductions in the number of offspring and the malformations observed in the experimental groups suggest that S. fissuratum affects fetal development and is teratogenic.
@ 2015 Elsevier Ltd. All rights reserved. |
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Palabras claves : |
ABORTIONS; POISONOUS PLANTS; STRYPHNODENDRON FISSURATUM; TERATOGENESIS. |
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Asunto categoría : |
-- |
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Marc : |
LEADER 02107naa a2200277 a 4500
001 1053971
005 2021-06-24
008 2015 bl uuuu u00u1 u #d
022 $a0041-0101
024 7 $a10.1016/j.toxicon.2015.09.003$2DOI
100 1 $aMACEDO, J.S.
245 $aCongenital malformations caused by Stryphnodendron fissuratum (Leg. Mimosoideae) in guinea pigs (Cavia porcellus).$h[electronic resource]
260 $c2015
520 $aABSTRACT. The aim of this study was to evaluate the toxicity of Stryphnodendron fissuratum pods in guinea pigs (Cavia porcellus) and test the hypothesis that this plant has teratogenic effects. Thus, sixteen guinea pigs were randomly divided into four groups of four animals each. Groups 10, 20 and 40 consisted of guinea pigs that received commercial food that contained crushed pods of S. fissuratum at concentrations of 10, 20 and 40 g/kg, respectively, during the period of organogenesis. Control group consisted of guinea pigs under the same management conditions that did not receive crushed pods of S. fissuratum in their food. In all experimental groups, the main clinical signs of poisoning consisted of anorexia, prostration, absence of vocalizations, alopecia, diarrhea, and abortions within the adult guinea pigs. Those that did not abort gave birth to weak, malnourished pups, some of which had fetal malformations. The main teratogenic changes consisted of eventration, arthrogryposis, amelia of the forelimbs, anophthalmia, microphthalmia, anotia and agnathia. The reductions in the number of offspring and the malformations observed in the experimental groups suggest that S. fissuratum affects fetal development and is teratogenic. @ 2015 Elsevier Ltd. All rights reserved.
653 $aABORTIONS
653 $aPOISONOUS PLANTS
653 $aSTRYPHNODENDRON FISSURATUM
653 $aTERATOGENESIS
700 1 $aROCHA, B.P.
700 1 $aCOLODEL, E.M.
700 1 $aFREITAS, S.H.
700 1 $aDORIA, R.G.S.
700 1 $aRIET-CORREA, F.
700 1 $aEVENCIO-NETO, J.
700 1 $aMENDONCA, F.S.
773 $tToxicon, 2015$gv. 106, p. 68-71.
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| 1. |  | TORTEREAU, F.; MARIE-ETANCELIN, C.; FRUTOS, P.; CONINGTON, J.; ARSENOS, G.; DE BARBIERI, I.; JAKOBSEN, J. H.; MORENO-ROMIEUX, C.; ARRANZ, J.J. SMARTER - Which novel traits to improve feed efficiency? [conference+oral presentation]. In: Proceedings of the 44th ICAR Annual Conference virtually held from Leeuwarden, NL, 26-30 April 2021. "Circular farming and its impact on animal genetics, animal recording of data and cattle / herd management". Editors: G. de Jong, K. de Koning, H. van den Bijgaart, M. Burke and C. Mosconi. (ICAR Technical Series no. 25).| Tipo: Trabajos en Congresos/Conferencias |
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| 2. | | TORTEREAU, F.; FRUTOS, P.; MARIE-ETANCELIN, C.; CONINGTON, J.; ARSENOS, G.; DE BARBIERI, I.; JAKOBSEN, J. H.; MORENO-ROMIEUX, C.; ARRANZ, J.J. SMARTER - Which novel traits to improve feed efficiency? 14. Resilience and Efficiency in Small Ruminants. In: Abstracts of the ICAR-Interbull Virtual Conference, Leeuwarden (Netherlands), April 26-30, 2021.| Tipo: Abstracts/Resúmenes |
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