02654naa a2200301 a 450000100080000000500110000800800410001902400360006010000310009624501270012726000090025450001140026352016850037765000210206265000150208365000260209865000200212465300140214465300190215865300090217770000160218670000160220270000150221870000160223370000130224970000270226277300630228910285932019-08-08       2017    bl uuuu     u00u1 u    #d7 a10.1016/j.rvsc.2017.07.0142DOI1 aANDRIGHETTO CANOZZIA, M.E.  aA meta-analysis of cortisol concentration, vocalization, and average daily gain associated with castration in beef cattle.  c2017  aArticle history: Received: 21 December 2016 // Received in revised form: 4 July 2017 // Accepted 16 July 2017  aA systematic review and meta-analysis (MA) were performed to summarize all scientific evidence for the effects of castration in male beef cattle on welfare indicators based on cortisol concentration, average daily gain (ADG), and vocalization. We searched five electronic databases, conference proceedings, and experts were contacted electronically. The main inclusion criteria involved completed studies using beef cattle up to one year of age undergoing surgical and non-surgical castration that presented cortisol concentration, ADG, or vocalization as an outcome. A random effect MA was conducted for each indicator separately with the mean of the control and treated groups. A total of 20 publications reporting 26 studies and 162 trials were included in the MA involving 1814 cattle. Between study heterogeneity was observed when analysing cortisol (I2 =56.7%) and ADG (I2 =79.6%). Surgical and non-surgical castration without drug administration compared to uncastrated animals showed no change (P?0.05) in cortisol level. Multimodal therapy for pain did not decrease (P ?0.05) cortisol concentration after 30 min when non-surgical castration was performed. Comparison between surgical castration, with and without anaesthesia, showed a tendency (P=0.077) to decrease cortisol levels after 120 min of intervention. Non-surgical and surgical castration, performed with no pain mitigation, increased and tended to increase the ADG by 0.814 g/d (P=0.001) and by 0.140 g/d (P=0.091), respectively, when compared to a non-castrated group. Our MA study demonstrates an inconclusive result to draw recommendations on preferred castration practices to minimize pain in beef cattle.  aBIENESTAR ANIMAL  aCASTRACION  aCIENCIAS VETERINARIAS  aGANADO DE CARNE  aANALGESIA  aANIMAL WELFARE  aPAIN1 aMEDEROS, A.1 aMANTECA, X.1 aTURNER, S.1 aMCMANUS, C.1 aZAGO, D.1 aJARDIM BARCELLOS, J.O.  tResearch in Veterinary Science, 2017, no. 114, p. 430-443.