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 | Acceso al texto completo restringido a Biblioteca INIA Las Brujas. Por información adicional contacte bibliolb@inia.org.uy. |
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Registro completo
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Biblioteca (s) : |
INIA Las Brujas. |
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Fecha : |
04/10/2014 |
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Actualizado : |
10/02/2020 |
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Tipo de producción científica : |
Artículos en Revistas Indexadas Internacionales |
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Autor : |
AGUILAR, I.; MISZTAL, I.; LEGARRA, A.; TSURUTA, S. |
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Afiliación : |
IGNACIO AGUILAR GARCIA, Instituto Nacional de Investigación Agropecuaria (INIA), Uruguay. |
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Título : |
Efficient computation of the genomic relationship matrix and other matrices used in single-step evaluation. |
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Fecha de publicación : |
2011 |
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Fuente / Imprenta : |
Journal of Animal Breeding and Genetics, 2011, v.128, no.6, p.422-428. |
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ISSN : |
0931-2668 |
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DOI : |
10.1111/j.1439-0388.2010.00912.x |
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Idioma : |
Inglés |
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Contenido : |
ABSTRACT.
Genomic evaluations can be calculated using a unified procedure that combines phenotypic, pedigree and genomic information. Implementation of such a procedure requires the inverse of the relationship matrix based on pedigree and genomic relationships. The objective of this study was to investigate efficient computing options to create relationship matrices based on genomic markers and pedigree information as well as their inverses. SNP maker information was simulated for a panel of 40K SNPs, with the number of genotyped animals up to 30000. Matrix multiplication in the computation of the genomic relationship was by a simple 'do' loop, by two optimized versions of the loop, and by a specific matrix multiplication subroutine. Inversion was by a generalized inverse algorithm and by a LAPACK subroutine. With the most efficient choices and parallel processing, creation of matrices for 30000 animals would take a few hours. Matrices required to implement a unified approach can be computed efficiently. Optimizations can be either by modifications of existing code or by the use of efficient automatic optimizations provided by open source or third-party libraries.
© 2011 Blackwell Verlag GmbH. |
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Thesagro : |
MEJORAMIENTO GENÉTICO ANIMAL; MODELOS MATEMÁTICOS; SELECCIÓN GENÓMICA. |
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Asunto categoría : |
L10 Genética y mejoramiento animal |
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Marc : |
LEADER 01921naa a2200217 a 4500
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005 2020-02-10
008 2011 bl uuuu u00u1 u #d
022 $a0931-2668
024 7 $a10.1111/j.1439-0388.2010.00912.x$2DOI
100 1 $aAGUILAR, I.
245 $aEfficient computation of the genomic relationship matrix and other matrices used in single-step evaluation.$h[electronic resource]
260 $c2011
520 $aABSTRACT. Genomic evaluations can be calculated using a unified procedure that combines phenotypic, pedigree and genomic information. Implementation of such a procedure requires the inverse of the relationship matrix based on pedigree and genomic relationships. The objective of this study was to investigate efficient computing options to create relationship matrices based on genomic markers and pedigree information as well as their inverses. SNP maker information was simulated for a panel of 40K SNPs, with the number of genotyped animals up to 30000. Matrix multiplication in the computation of the genomic relationship was by a simple 'do' loop, by two optimized versions of the loop, and by a specific matrix multiplication subroutine. Inversion was by a generalized inverse algorithm and by a LAPACK subroutine. With the most efficient choices and parallel processing, creation of matrices for 30000 animals would take a few hours. Matrices required to implement a unified approach can be computed efficiently. Optimizations can be either by modifications of existing code or by the use of efficient automatic optimizations provided by open source or third-party libraries. © 2011 Blackwell Verlag GmbH.
650 $aMEJORAMIENTO GENÉTICO ANIMAL
650 $aMODELOS MATEMÁTICOS
650 $aSELECCIÓN GENÓMICA
700 1 $aMISZTAL, I.
700 1 $aLEGARRA, A.
700 1 $aTSURUTA, S.
773 $tJournal of Animal Breeding and Genetics, 2011$gv.128, no.6, p.422-428.
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Registro original : |
INIA Las Brujas (LB) |
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| Acceso al texto completo restringido a Biblioteca INIA Tacuarembó. Por información adicional contacte bibliotb@tb.inia.org.uy. |
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Registro completo
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Biblioteca (s) : |
INIA Tacuarembó. |
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Fecha actual : |
21/02/2014 |
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Actualizado : |
08/08/2019 |
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Tipo de producción científica : |
Artículos en Revistas Indexadas Internacionales |
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Circulación / Nivel : |
Internacional - -- |
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Autor : |
ANDRIGHETTO CANOZZIA, M.E.; MEDEROS, A.; MANTECA, X.; TURNER, S.; MCMANUS, C.; ZAGO, D.; JARDIM BARCELLOS, J.O. |
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Afiliación : |
MARÍA EUGENIA ANDRIGHETTO CANOZZIA, Department of Animal Science, Federal University of Rio Grande do Sul.; AMERICA ESTHER MEDEROS SILVEIRA, INIA (Instituto Nacional de Investigación Agropecuaria), Uruguay; XAVIER MANTECA, Department of Animal and Food Science, School of Veterinary Science, Universitat Autònoma de Barcelona.; SIMON TURNER, Animal and Veterinary Sciences Group, Scotland's Rural College.; CONCEPTA MCMANUS, Institute of Biological Sciences, University of Brasilia.; DANIELE ZAGO, Department of Animal Science, Federal University of Rio Grande do Sul.; JÚLIO OTÁVIO JARDIM BARCELLOS, Department of Animal Science, Federal University of Rio Grande do Sul. |
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Título : |
A meta-analysis of cortisol concentration, vocalization, and average daily gain associated with castration in beef cattle. |
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Fecha de publicación : |
2017 |
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Fuente / Imprenta : |
Research in Veterinary Science, 2017, no. 114, p. 430-443. |
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DOI : |
10.1016/j.rvsc.2017.07.014 |
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Idioma : |
Inglés |
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Notas : |
Article history: Received: 21 December 2016 // Received in revised form: 4 July 2017 // Accepted 16 July 2017 |
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Contenido : |
A systematic review and meta-analysis (MA) were performed to summarize all scientific evidence for the effects of castration in male beef cattle on welfare indicators based on cortisol concentration, average daily gain (ADG), and vocalization. We searched five electronic databases, conference proceedings, and experts were contacted
electronically. The main inclusion criteria involved completed studies using beef cattle up to one year of age undergoing surgical and non-surgical castration that presented cortisol concentration, ADG, or vocalization as an outcome. A random effect MA was conducted for each indicator separately with the mean of the control and
treated groups. A total of 20 publications reporting 26 studies and 162 trials were included in the MA involving 1814 cattle. Between study heterogeneity was observed when analysing cortisol (I2 =56.7%) and ADG (I2 =79.6%). Surgical and non-surgical castration without drug administration compared to uncastrated animals
showed no change (P?0.05) in cortisol level. Multimodal therapy for pain did not decrease (P ?0.05) cortisol concentration after 30 min when non-surgical castration was performed. Comparison between surgical castration, with and without anaesthesia, showed a tendency (P=0.077) to decrease cortisol levels after 120 min of intervention. Non-surgical and surgical castration, performed with no pain mitigation, increased and tended to increase the ADG by 0.814 g/d (P=0.001) and by 0.140 g/d (P=0.091), respectively, when compared to a non-castrated group. Our MA study demonstrates an inconclusive result to draw recommendations on preferred castration practices to minimize pain in beef cattle. MenosA systematic review and meta-analysis (MA) were performed to summarize all scientific evidence for the effects of castration in male beef cattle on welfare indicators based on cortisol concentration, average daily gain (ADG), and vocalization. We searched five electronic databases, conference proceedings, and experts were contacted
electronically. The main inclusion criteria involved completed studies using beef cattle up to one year of age undergoing surgical and non-surgical castration that presented cortisol concentration, ADG, or vocalization as an outcome. A random effect MA was conducted for each indicator separately with the mean of the control and
treated groups. A total of 20 publications reporting 26 studies and 162 trials were included in the MA involving 1814 cattle. Between study heterogeneity was observed when analysing cortisol (I2 =56.7%) and ADG (I2 =79.6%). Surgical and non-surgical castration without drug administration compared to uncastrated animals
showed no change (P?0.05) in cortisol level. Multimodal therapy for pain did not decrease (P ?0.05) cortisol concentration after 30 min when non-surgical castration was performed. Comparison between surgical castration, with and without anaesthesia, showed a tendency (P=0.077) to decrease cortisol levels after 120 min of intervention. Non-surgical and surgical castration, performed with no pain mitigation, increased and tended to increase the ADG by 0.814 g/d (P=0.001) and by 0.140 g/d (P=0.091), respectively... Presentar Todo |
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Palabras claves : |
ANALGESIA; ANIMAL WELFARE; PAIN. |
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Thesagro : |
BIENESTAR ANIMAL; CASTRACION; CIENCIAS VETERINARIAS; GANADO DE CARNE. |
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Asunto categoría : |
L70 Ciencias veterinarias e higiene - Aspectos generales |
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Marc : |
LEADER 02654naa a2200301 a 4500
001 1028593
005 2019-08-08
008 2017 bl uuuu u00u1 u #d
024 7 $a10.1016/j.rvsc.2017.07.014$2DOI
100 1 $aANDRIGHETTO CANOZZIA, M.E.
245 $aA meta-analysis of cortisol concentration, vocalization, and average daily gain associated with castration in beef cattle.
260 $c2017
500 $aArticle history: Received: 21 December 2016 // Received in revised form: 4 July 2017 // Accepted 16 July 2017
520 $aA systematic review and meta-analysis (MA) were performed to summarize all scientific evidence for the effects of castration in male beef cattle on welfare indicators based on cortisol concentration, average daily gain (ADG), and vocalization. We searched five electronic databases, conference proceedings, and experts were contacted electronically. The main inclusion criteria involved completed studies using beef cattle up to one year of age undergoing surgical and non-surgical castration that presented cortisol concentration, ADG, or vocalization as an outcome. A random effect MA was conducted for each indicator separately with the mean of the control and treated groups. A total of 20 publications reporting 26 studies and 162 trials were included in the MA involving 1814 cattle. Between study heterogeneity was observed when analysing cortisol (I2 =56.7%) and ADG (I2 =79.6%). Surgical and non-surgical castration without drug administration compared to uncastrated animals showed no change (P?0.05) in cortisol level. Multimodal therapy for pain did not decrease (P ?0.05) cortisol concentration after 30 min when non-surgical castration was performed. Comparison between surgical castration, with and without anaesthesia, showed a tendency (P=0.077) to decrease cortisol levels after 120 min of intervention. Non-surgical and surgical castration, performed with no pain mitigation, increased and tended to increase the ADG by 0.814 g/d (P=0.001) and by 0.140 g/d (P=0.091), respectively, when compared to a non-castrated group. Our MA study demonstrates an inconclusive result to draw recommendations on preferred castration practices to minimize pain in beef cattle.
650 $aBIENESTAR ANIMAL
650 $aCASTRACION
650 $aCIENCIAS VETERINARIAS
650 $aGANADO DE CARNE
653 $aANALGESIA
653 $aANIMAL WELFARE
653 $aPAIN
700 1 $aMEDEROS, A.
700 1 $aMANTECA, X.
700 1 $aTURNER, S.
700 1 $aMCMANUS, C.
700 1 $aZAGO, D.
700 1 $aJARDIM BARCELLOS, J.O.
773 $tResearch in Veterinary Science, 2017, no. 114, p. 430-443.
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